CRCGN016_MCF10A.WT.HP_24H:J01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tiabendazole 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 3.51047
PPARG peroxisome proliferator-activated receptor gamma 3.33199
NUP133 nucleoporin 133kDa 2.56205
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.51183
PRR7 proline rich 7 (synaptic) 2.36828
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.13391
HMOX1 heme oxygenase 1 2.12983
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.11157

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -5.01374
DYNLT3 dynein, light chain, Tctex-type 3 -4.48359
UFM1 ubiquitin-fold modifier 1 -3.51828
CCNB1 cyclin B1 -3.39137
OXA1L oxidase (cytochrome c) assembly 1-like -3.20901
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.9422
ARID4B AT rich interactive domain 4B (RBP1-like) -2.68401
COG2 component of oligomeric golgi complex 2 -2.32861
FAIM Fas apoptotic inhibitory molecule -2.26606
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.26311
GADD45B growth arrest and DNA-damage-inducible, beta -2.19099
RPIA ribose 5-phosphate isomerase A -2.17294