CRCGN016_MCF10A.WT.HP_24H:J06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dioxane 11.44 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LYN LYN proto-oncogene, Src family tyrosine kinase 4.43003
EAPP E2F-associated phosphoprotein 3.52034
ACAA1 acetyl-CoA acyltransferase 1 3.15114
HBA1 hemoglobin, alpha 1 3.09249
MEF2C myocyte enhancer factor 2C 2.81976
FBXL12 F-box and leucine-rich repeat protein 12 2.72364
WIF1 WNT inhibitory factor 1 2.71601
MTMR11 myotubularin related protein 11 2.53637
FGFR4 fibroblast growth factor receptor 4 2.25142
TCTN1 tectonic family member 1 2.24483
LGMN legumain 2.19343
PLSCR3 phospholipid scramblase 3 2.18095
CCDC85B coiled-coil domain containing 85B 2.14608
CDCA4 cell division cycle associated 4 2.05987

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.31616
UFM1 ubiquitin-fold modifier 1 -4.60104
TEX10 testis expressed 10 -4.11004
PCCB propionyl CoA carboxylase, beta polypeptide -3.82998
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.37492
HSPA8 heat shock 70kDa protein 8 -3.11565
OXA1L oxidase (cytochrome c) assembly 1-like -3.02364
DSG2 desmoglein 2 -2.45216
ANXA2 annexin A2 -2.37388
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.12955
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough -2.02506