CRCGN016_MCF10A.WT.HP_24H:J09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isopropyl-n-(3-chloro?phenyl)carbamate 10.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 3.7833
GRB10 growth factor receptor-bound protein 10 3.38318
PECR peroxisomal trans-2-enoyl-CoA reductase 3.26505
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.94745
IGHMBP2 immunoglobulin mu binding protein 2 2.6967
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.34405
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.2635
TXNL4B thioredoxin-like 4B 2.21745
E2F6 E2F transcription factor 6 2.02845

decreased expression

Symbol Name Standardized Value
DCK deoxycytidine kinase -4.7765
C2CD5 C2 calcium-dependent domain containing 5 -4.7155
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.40505
ANXA2 annexin A2 -3.64723
NUSAP1 nucleolar and spindle associated protein 1 -2.89593
HRAS Harvey rat sarcoma viral oncogene homolog -2.2924
STXBP2 syntaxin binding protein 2 -2.1401
PPIB peptidylprolyl isomerase B (cyclophilin B) -2.1028
UBE2A ubiquitin-conjugating enzyme E2A -2.05443
HSPA1A heat shock 70kDa protein 1A -2.04895