CRCGN016_MCF10A.WT.HP_24H:J12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethylnitrosamine 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.91958
WFS1 Wolfram syndrome 1 (wolframin) 4.82546
HBA1 hemoglobin, alpha 1 4.31582
KDM5D lysine (K)-specific demethylase 5D 3.14148
ACAA1 acetyl-CoA acyltransferase 1 2.94218
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.88054
STK10 serine/threonine kinase 10 2.68686
COMP cartilage oligomeric matrix protein 2.59266
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.40225
CARMIL1 capping protein regulator and myosin 1 linker 1 2.36716
HYOU1 hypoxia up-regulated 1 2.2703
UGP2 UDP-glucose pyrophosphorylase 2 2.10574
NOTCH1 notch 1 2.05167

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -7.05177
KIF14 kinesin family member 14 -4.79499
SMC1A structural maintenance of chromosomes 1A -3.76098
KDM5C lysine (K)-specific demethylase 5C -2.83066
SGK1 serum/glucocorticoid regulated kinase 1 -2.62491
HMG20B high mobility group 20B -2.38874
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.34512
BASP1 brain abundant, membrane attached signal protein 1 -2.31936
USP9X ubiquitin specific peptidase 9, X-linked -2.24763
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.23277
OFD1 oral-facial-digital syndrome 1 -2.21183
PUDP pseudouridine 5'-phosphatase -2.10634