CRCGN016_MCF10A.WT.HP_24H:J13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 94.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.83869
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.66301
EAPP E2F-associated phosphoprotein 3.27375
ACAA1 acetyl-CoA acyltransferase 1 2.94507
AMDHD2 amidohydrolase domain containing 2 2.88589
THAP12 THAP domain containing 12 2.67779
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.59636
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.56289
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.48969
TBX2 T-box 2 2.37227
COMP cartilage oligomeric matrix protein 2.15243

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -6.55838
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.50969
DNM1L dynamin 1-like -3.92456
SCYL3 SCY1-like 3 (S. cerevisiae) -3.17956
DSG2 desmoglein 2 -2.92406
S100A8 S100 calcium binding protein A8 -2.63179
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.60274
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.44784
FASN fatty acid synthase -2.42879
TIMP1 TIMP metallopeptidase inhibitor 1 -2.33992
SGK1 serum/glucocorticoid regulated kinase 1 -2.11183