CRCGN016_MCF10A.WT.HP_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 31.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.87798
INTS3 integrator complex subunit 3 3.73874
GET1 guided entry of tail-anchored proteins factor 1 3.66991
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.57005
LOXL1 lysyl oxidase-like 1 3.40489
KIF5C kinesin family member 5C 2.81883
MTA2 metastasis associated 1 family, member 2 2.68333
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.43543
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.41927
WDR76 WD repeat domain 76 2.36043
THRAP3 thyroid hormone receptor associated protein 3 2.29946
COMP cartilage oligomeric matrix protein 2.16321
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.01746

decreased expression

Symbol Name Standardized Value
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.86622
HMG20B high mobility group 20B -3.72306
DSG2 desmoglein 2 -3.52609
STXBP2 syntaxin binding protein 2 -3.46457
BASP1 brain abundant, membrane attached signal protein 1 -3.45082
KRT14 keratin 14, type I -3.19789
ARID4B AT rich interactive domain 4B (RBP1-like) -3.12419
HSPA8 heat shock 70kDa protein 8 -3.05381
ANXA2 annexin A2 -2.74709
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.7359
SCAND1 SCAN domain containing 1 -2.47282
SGK1 serum/glucocorticoid regulated kinase 1 -2.36969
ADI1 acireductone dioxygenase 1 -2.35857
TUBB6 tubulin, beta 6 class V -2.2406
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.17655
PLK1 polo-like kinase 1 -2.15037
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.13236
GDF15 growth differentiation factor 15 -2.07377
CD8A CD8a molecule -2.03935