CRCGN016_MCF10A.WT.HP_24H:J15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 10.53 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 4.10195
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.06806
CCP110 centriolar coiled coil protein 110kDa 3.8848
AGR2 anterior gradient 2 3.77516
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.49989
TBX2 T-box 2 3.32376
HBA1 hemoglobin, alpha 1 3.30212
ADGRE5 adhesion G protein-coupled receptor E5 3.21939
FZD7 frizzled class receptor 7 3.16501
SNAP25 synaptosomal-associated protein, 25kDa 3.09002
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.85808
VAV3 vav 3 guanine nucleotide exchange factor 2.79356
NEFM neurofilament, medium polypeptide 2.51995
STMN2 stathmin 2 2.39045
WIF1 WNT inhibitory factor 1 2.38879
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.27811
CADM1 cell adhesion molecule 1 2.25209
TASP1 taspase, threonine aspartase, 1 2.11893
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.07329

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.50671
UBE3C ubiquitin protein ligase E3C -4.34028
LAP3 leucine aminopeptidase 3 -4.10921
SGK1 serum/glucocorticoid regulated kinase 1 -3.66417
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.21908
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.6893
MSN moesin -2.45809
HTRA1 HtrA serine peptidase 1 -2.13726