CRCGN016_MCF10A.WT.HP_24H:J16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.63316
PPARG peroxisome proliferator-activated receptor gamma 4.09918
KLHL21 kelch-like family member 21 3.02569
ABHD4 abhydrolase domain containing 4 2.92253
TBX2 T-box 2 2.9104
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.73773
INTS3 integrator complex subunit 3 2.73763
ABHD6 abhydrolase domain containing 6 2.59009
ZW10 zw10 kinetochore protein 2.51179
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.45349
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.42491
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.07443

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -3.80597
GDF15 growth differentiation factor 15 -3.74512
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.41441
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.63836
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.58901
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.56297
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.23795
BAD BCL2-associated agonist of cell death -2.07559
REXO2 RNA exonuclease 2 -2.04455
BASP1 brain abundant, membrane attached signal protein 1 -2.0118