CRCGN016_MCF10A.WT.HP_24H:J17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.69191
AGR2 anterior gradient 2 4.01901
AXIN1 axin 1 3.56459
OLFML2B olfactomedin-like 2B 3.30999
CHMP6 charged multivesicular body protein 6 2.97124
ACAA1 acetyl-CoA acyltransferase 1 2.95829
ZMIZ1 zinc finger, MIZ-type containing 1 2.8282
PPARG peroxisome proliferator-activated receptor gamma 2.60575
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.33164
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.31296
MYLK myosin light chain kinase 2.29552

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -4.73785
PRPF4 pre-mRNA processing factor 4 -4.38325
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.97485
UFM1 ubiquitin-fold modifier 1 -2.62116
ANXA2 annexin A2 -2.4197
NGRN neugrin, neurite outgrowth associated -2.00652