CRCGN016_MCF10A.WT.HP_24H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

68 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 6.40278
KDM5D lysine (K)-specific demethylase 5D 3.81819
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 3.60343
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.56154
NSG2 neuronal vesicle trafficking associated 2 3.54619
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 3.48002
SYN1 synapsin I 3.4686
SPAG4 sperm associated antigen 4 3.39235
LOXL1 lysyl oxidase-like 1 3.32044
OLFM1 olfactomedin 1 3.21591
SMIM40 small integral membrane protein 40 3.08212
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.0111
NEFM neurofilament, medium polypeptide 3.00678
STMN2 stathmin 2 3.00317
CARTPT CART prepropeptide 2.90211
VSNL1 visinin-like 1 2.84574
NEFL neurofilament, light polypeptide 2.81601
USP9Y ubiquitin specific peptidase 9, Y-linked 2.7424
SNAP91 synaptosomal-associated protein, 91kDa 2.7224
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.69388
RGS7 regulator of G-protein signaling 7 2.67349
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.634
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.62589
ZFY zinc finger protein, Y-linked 2.58494
IGHMBP2 immunoglobulin mu binding protein 2 2.54628
SYT1 synaptotagmin I 2.54132
SCG3 secretogranin III 2.53564
CHGB chromogranin B 2.51793
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.49393
RPH3A rabphilin 3A 2.48632
RUNDC3A RUN domain containing 3A 2.38399
DENND1C DENN/MADD domain containing 1C 2.37994
MYT1L myelin transcription factor 1-like 2.36466
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.3565
SNCB synuclein, beta 2.32038
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.31272
GRM6 glutamate receptor, metabotropic 6 2.2171
NLGN4Y neuroligin 4, Y-linked 2.21584
ACTL6B actin-like 6B 2.18627
RANBP17 RAN binding protein 17 2.18398
SV2B synaptic vesicle glycoprotein 2B 2.18158
CBLN1 cerebellin 1 precursor 2.1741
CNTN1 contactin 1 2.15288
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.14382
FSCN3 fascin actin-bundling protein 3, testicular 2.13642
TESMIN testis expressed metallothionein like protein 2.13409
GDAP1 ganglioside induced differentiation associated protein 1 2.07914
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.07559
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.07206
PCSK1 proprotein convertase subtilisin/kexin type 1 2.06501
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.03146

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.79226
SLC35F2 solute carrier family 35, member F2 -3.50251
CAB39 calcium binding protein 39 -3.37649
MSN moesin -3.19035
HMG20B high mobility group 20B -3.07334
ENOPH1 enolase-phosphatase 1 -2.81598
CD320 CD320 molecule -2.72772
THAP11 THAP domain containing 11 -2.66188
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.51034
KDM5C lysine (K)-specific demethylase 5C -2.41215
PLK1 polo-like kinase 1 -2.32521
SGK1 serum/glucocorticoid regulated kinase 1 -2.16694
TMEM115 transmembrane protein 115 -2.11709
MYO5A myosin VA (heavy chain 12, myoxin) -2.11111
SMC1A structural maintenance of chromosomes 1A -2.04888
GPR137B G protein-coupled receptor 137B -2.04676
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.0103