CRCGN016_MCF10A.WT.HP_24H:J19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 102.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.00106
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.7303
UBQLN2 ubiquilin 2 3.25353
ACLY ATP citrate lyase 2.92508
BAMBI BMP and activin membrane-bound inhibitor 2.83974
MAMLD1 mastermind-like domain containing 1 2.10646
DENND2D DENN/MADD domain containing 2D 2.08685
ZBTB35 zinc finger and BTB domain containing 35 2.07357

decreased expression

Symbol Name Standardized Value
TIMP1 TIMP metallopeptidase inhibitor 1 -4.70848
GDF15 growth differentiation factor 15 -4.48684
KRT14 keratin 14, type I -4.00013
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.81832
EXOSC4 exosome component 4 -3.78777
TEX10 testis expressed 10 -3.76032
BAG3 BCL2-associated athanogene 3 -3.64741
HMG20B high mobility group 20B -3.63936
ARID4B AT rich interactive domain 4B (RBP1-like) -3.44533
MT1X metallothionein 1X -3.42085
KIF14 kinesin family member 14 -3.39717
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.69671
ANKRD10 ankyrin repeat domain 10 -2.05503