CRCGN016_MCF10A.WT.HP_24H:J20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 34.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 4.01997
PEX11A peroxisomal biogenesis factor 11 alpha 3.43545
FGFR4 fibroblast growth factor receptor 4 2.65398
APOE apolipoprotein E 2.59228
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.4727
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.14329
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.07044

decreased expression

Symbol Name Standardized Value
LAP3 leucine aminopeptidase 3 -3.50528
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.47681
GDF15 growth differentiation factor 15 -3.348
KRT14 keratin 14, type I -3.06442
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.78829
RNF167 ring finger protein 167 -2.6576
NVL nuclear VCP-like -2.51776
CREB1 cAMP responsive element binding protein 1 -2.48734
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.02992