CRCGN016_MCF10A.WT.HP_24H:J22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pyrazinamide 99.96 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 6.17856
VAV3 vav 3 guanine nucleotide exchange factor 4.28077
C2CD2 C2 calcium-dependent domain containing 2 3.37152
EVL Enah/Vasp-like 3.32123
SPAG4 sperm associated antigen 4 3.2707
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.26357
CCL2 chemokine (C-C motif) ligand 2 2.54636
FOXC1 forkhead box C1 2.23857
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.01394

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.57387
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.64061
TRIB3 tribbles pseudokinase 3 -3.43971
DERA deoxyribose-phosphate aldolase (putative) -3.09239
HMG20B high mobility group 20B -3.0166
TENT4A terminal nucleotidyltransferase 4A -2.80682
CLTB clathrin, light chain B -2.57956
S100A8 S100 calcium binding protein A8 -2.27142
ZNF354A zinc finger protein 354A -2.22993
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.12239