CRCGN016_MCF10A.WT.HP_24H:K02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phthalamide 33.43 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

39 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 5.45115
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.00126
ADAM10 ADAM metallopeptidase domain 10 4.65388
PPARG peroxisome proliferator-activated receptor gamma 4.38822
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.19021
AGR2 anterior gradient 2 3.91665
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.89313
FZD2 frizzled class receptor 2 3.2172
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.99241
LPL lipoprotein lipase 2.82485
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.66793
MINDY2 MINDY lysine 48 deubiquitinase 2 2.60301
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 2.45902
CCL2 chemokine (C-C motif) ligand 2 2.39709
NRBF2 nuclear receptor binding factor 2 2.28656
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.22017
IL7R interleukin 7 receptor 2.20705
TCTA T-cell leukemia translocation altered 2.18192
CNPY3 canopy FGF signaling regulator 3 2.07459
TLCD3A TLC domain containing 3A 2.03511
TSPAN8 tetraspanin 8 2.01536

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -5.08082
CHIC2 cysteine-rich hydrophobic domain 2 -4.78307
TXNDC9 thioredoxin domain containing 9 -4.76286
LYPLA1 lysophospholipase I -4.57193
NT5DC2 5'-nucleotidase domain containing 2 -4.32661
MRPL15 mitochondrial ribosomal protein L15 -2.8753
RXYLT1 ribitol xylosyltransferase 1 -2.86727
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.78889
LIPT1 lipoyltransferase 1 -2.65175
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -2.52548
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.38976
RBFA ribosome binding factor A (putative) -2.30097
UNC50 unc-50 homolog (C. elegans) -2.30088
TRPS1 trichorhinophalangeal syndrome I -2.28314
CAMLG calcium modulating ligand -2.26893
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.11048
RASL11B RAS-like, family 11, member B -2.06786
GRAMD2B GRAM domain containing 2B -2.0206