CRCGN016_MCF10A.WT.HP_24H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phthalamide 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 5.44126
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.12752
CHMP6 charged multivesicular body protein 6 4.37792
CCL2 chemokine (C-C motif) ligand 2 3.30139
TLR4 toll-like receptor 4 2.96891
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.96725
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.71763
MAMLD1 mastermind-like domain containing 1 2.28293
ESM1 endothelial cell-specific molecule 1 2.19762
CXCR4 chemokine (C-X-C motif) receptor 4 2.03883
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.00395

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -3.15458
KIF14 kinesin family member 14 -3.00483
KDM3A lysine (K)-specific demethylase 3A -2.80331
LAP3 leucine aminopeptidase 3 -2.72541
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.61472
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.42
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.35596
HMG20B high mobility group 20B -2.18765
ANO10 anoctamin 10 -2.00691