CRCGN016_MCF10A.WT.HP_24H:K11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description wortmannin 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

589 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 5.97578
LOXL1 lysyl oxidase-like 1 5.3182
AGR2 anterior gradient 2 4.158
GAA glucosidase, alpha; acid 4.08595
FAT1 FAT atypical cadherin 1 4.0655
STK10 serine/threonine kinase 10 4.02282
IRF9 interferon regulatory factor 9 3.88144
TNIP1 TNFAIP3 interacting protein 1 3.78261
VAT1 vesicle amine transport 1 3.7746
RALGDS ral guanine nucleotide dissociation stimulator 3.75653
GHR growth hormone receptor 3.68206
FHL2 four and a half LIM domains 2 3.56952
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.53902
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.49235
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.45054
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.43119
IL1B interleukin 1, beta 3.40341
ADRB2 adrenoceptor beta 2, surface 3.31965
NOP53 NOP53 ribosome biogenesis factor 3.31345
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 3.23528
SMAD3 SMAD family member 3 3.23366
RAB21 RAB21, member RAS oncogene family 3.18134
BLCAP bladder cancer associated protein 3.16499
MVP major vault protein 3.16106
NPDC1 neural proliferation, differentiation and control, 1 3.09523
SLC10A3 solute carrier family 10, member 3 3.08306
PTK2B protein tyrosine kinase 2 beta 3.07546
NT5E 5'-nucleotidase, ecto (CD73) 3.04071
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.03107
AVEN apoptosis, caspase activation inhibitor 2.97886
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.94494
TNS4 tensin 4 2.94317
CALCOCO1 calcium binding and coiled-coil domain 1 2.93
RABAC1 Rab acceptor 1 (prenylated) 2.90483
FAM50A family with sequence similarity 50, member A 2.89094
EDN1 endothelin 1 2.87841
FCHO1 FCH domain only 1 2.82889
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.82631
TPM1 tropomyosin 1 (alpha) 2.81202
EIF3L eukaryotic translation initiation factor 3, subunit L 2.78277
TMEM53 transmembrane protein 53 2.78133
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.77482
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.77278
LTBP4 latent transforming growth factor beta binding protein 4 2.76603
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.75891
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.75298
PACS2 phosphofurin acidic cluster sorting protein 2 2.74476
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.74025
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.71862
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.71753
TMEM43 transmembrane protein 43 2.71749
MUC2 mucin 2, oligomeric mucus/gel-forming 2.69149
ELMO3 engulfment and cell motility 3 2.67236
STX4 syntaxin 4 2.63062
CRELD2 cysteine-rich with EGF-like domains 2 2.62722
GEMIN8 gem (nuclear organelle) associated protein 8 2.62563
TSPAN4 tetraspanin 4 2.6221
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.61941
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.60737
GDI1 GDP dissociation inhibitor 1 2.60682
GFUS GDP-L-fucose synthase 2.5941
RAP1GAP RAP1 GTPase activating protein 2.58469
IRF3 interferon regulatory factor 3 2.5785
NRIP2 nuclear receptor interacting protein 2 2.576
GIPC2 GIPC PDZ domain containing family, member 2 2.57422
RAI2 retinoic acid induced 2 2.56016
SQOR sulfide quinone oxidoreductase 2.55865
VEGFB vascular endothelial growth factor B 2.55774
GSTA3 glutathione S-transferase alpha 3 2.55241
CLTB clathrin, light chain B 2.54672
LGALS4 lectin, galactoside-binding, soluble, 4 2.53939
TLCD3A TLC domain containing 3A 2.52957
STARD5 StAR-related lipid transfer (START) domain containing 5 2.52848
GZMM granzyme M (lymphocyte met-ase 1) 2.51345
MFAP5 microfibrillar associated protein 5 2.50347
DAAM1 dishevelled associated activator of morphogenesis 1 2.50335
COL17A1 collagen, type XVII, alpha 1 2.49601
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.492
NOPCHAP1 NOP protein chaperone 1 2.48457
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.48311
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.47898
DCAF4 DDB1 and CUL4 associated factor 4 2.47571
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.46386
CBX7 chromobox homolog 7 2.46241
SNAI2 snail family zinc finger 2 2.46115
ZNF696 zinc finger protein 696 2.45572
DOCK1 dedicator of cytokinesis 1 2.45261
SETBP1 SET binding protein 1 2.44625
TSC2 tuberous sclerosis 2 2.44513
LMF2 lipase maturation factor 2 2.44462
SCCPDH saccharopine dehydrogenase (putative) 2.44219
BSDC1 BSD domain containing 1 2.43222
GRAMD4 GRAM domain containing 4 2.42911
JAG1 jagged 1 2.4283
MAPK7 mitogen-activated protein kinase 7 2.41897
SPATA20 spermatogenesis associated 20 2.41299
NOX1 NADPH oxidase 1 2.40557
APP amyloid beta (A4) precursor protein 2.40265
RBM41 RNA binding motif protein 41 2.40072
FRYL FRY-like 2.39684
THBS3 thrombospondin 3 2.39185
BPHL biphenyl hydrolase-like (serine hydrolase) 2.39031
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.3771
TM9SF3 transmembrane 9 superfamily member 3 2.37242
PROS1 protein S (alpha) 2.37181
PYCARD PYD and CARD domain containing 2.37131
ITGB4 integrin, beta 4 2.37079
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.36712
IGBP1 immunoglobulin (CD79A) binding protein 1 2.36151
ZC3H12A zinc finger CCCH-type containing 12A 2.3605
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.36002
PTPRK protein tyrosine phosphatase, receptor type, K 2.3498
GJB5 gap junction protein, beta 5, 31.1kDa 2.343
ARSA arylsulfatase A 2.3423
MFGE8 milk fat globule-EGF factor 8 protein 2.34146
KIAA0040 KIAA0040 2.3411
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.34083
CD160 CD160 molecule 2.33341
TMEM35B transmembrane protein 35B 2.33288
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.33076
SH2D3C SH2 domain containing 3C 2.3289
DUSP7 dual specificity phosphatase 7 2.32372
OTC ornithine carbamoyltransferase 2.32154
GUCY2C guanylate cyclase 2C 2.30914
MYL9 myosin, light chain 9, regulatory 2.30696
NBEAL2 neurobeachin-like 2 2.30505
TAAR5 trace amine associated receptor 5 2.30481
GYPC glycophorin C (Gerbich blood group) 2.3039
PDE5A phosphodiesterase 5A, cGMP-specific 2.30002
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.29834
AMIGO2 adhesion molecule with Ig-like domain 2 2.2967
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.29599
CCL14 chemokine (C-C motif) ligand 14 2.29461
ARHGAP25 Rho GTPase activating protein 25 2.29296
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.29062
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.28463
MSI1 musashi RNA-binding protein 1 2.27963
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.27841
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.27592
CES2 carboxylesterase 2 2.27397
OLFM4 olfactomedin 4 2.27265
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.26996
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.26752
MYH9 myosin, heavy chain 9, non-muscle 2.26362
FAXDC2 fatty acid hydroxylase domain containing 2 2.26255
TMCC2 transmembrane and coiled-coil domain family 2 2.26203
MNT MAX network transcriptional repressor 2.25894
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.25874
ATOH1 atonal homolog 1 (Drosophila) 2.25809
GRHPR glyoxylate reductase/hydroxypyruvate reductase 2.25579
PCNT pericentrin 2.25443
IDUA iduronidase, alpha-L- 2.25241
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.25094
HMGA2 high mobility group AT-hook 2 2.24775
BTBD7 BTB (POZ) domain containing 7 2.24775
EEF1B2 eukaryotic translation elongation factor 1 beta 2 2.24694
POM121 POM121 transmembrane nucleoporin 2.24437
ANGPTL2 angiopoietin-like 2 2.24399
DGCR8 DGCR8 microprocessor complex subunit 2.24376
LRP10 low density lipoprotein receptor-related protein 10 2.24024
ZHX3 zinc fingers and homeoboxes 3 2.23926
ZNF611 zinc finger protein 611 2.23504
PALM2AKAP2 PALM2 and AKAP2 fusion 2.2321
TBX21 T-box 21 2.22455
DES desmin 2.22305
S100A13 S100 calcium binding protein A13 2.22146
EYA1 EYA transcriptional coactivator and phosphatase 1 2.22096
MMP23B matrix metallopeptidase 23B 2.21827
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.21761
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.21647
RAB36 RAB36, member RAS oncogene family 2.20717
CD247 CD247 molecule 2.20664
TNXB tenascin XB 2.19956
PTGIS prostaglandin I2 (prostacyclin) synthase 2.19798
STXBP2 syntaxin binding protein 2 2.19702
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.19492
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.19464
APOL3 apolipoprotein L, 3 2.19249
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.18495
FBXL8 F-box and leucine-rich repeat protein 8 2.18424
HDAC5 histone deacetylase 5 2.18207
MOSPD3 motile sperm domain containing 3 2.18174
CTSF cathepsin F 2.17949
LSP1 lymphocyte-specific protein 1 2.17687
PBLD phenazine biosynthesis-like protein domain containing 2.17245
EPS8L3 EPS8-like 3 2.17139
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.17081
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 2.16869
AHDC1 AT hook, DNA binding motif, containing 1 2.15812
POGLUT1 protein O-glucosyltransferase 1 2.15167
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.14247
NKG7 natural killer cell granule protein 7 2.14238
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 2.13811
ASIC1 acid sensing (proton gated) ion channel 1 2.13378
CSNK1E casein kinase 1, epsilon 2.13353
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.13244
TCTA T-cell leukemia translocation altered 2.13178
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 2.1277
ZNF667 zinc finger protein 667 2.12583
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.12155
DDR1 discoidin domain receptor tyrosine kinase 1 2.12088
ZBTB7A zinc finger and BTB domain containing 7A 2.12049
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.12014
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 2.11791
KIF13A kinesin family member 13A 2.11622
PRR7 proline rich 7 (synaptic) 2.11583
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.11474
EXO5 exonuclease 5 2.11463
GYPB glycophorin B (MNS blood group) 2.11145
INSM1 insulinoma-associated 1 2.11095
CHMP4B charged multivesicular body protein 4B 2.10995
MEAK7 MTOR associated protein, eak-7 homolog 2.10725
PDGFA platelet-derived growth factor alpha polypeptide 2.10493
PRDM12 PR domain containing 12 2.10487
RHEX regulator of hemoglobinization and erythroid cell expansion 2.10434
GPR161 G protein-coupled receptor 161 2.10309
TMEM40 transmembrane protein 40 2.102
PWP1 PWP1 homolog (S. cerevisiae) 2.10149
PVALB parvalbumin 2.10071
LDOC1 leucine zipper, down-regulated in cancer 1 2.09941
ECH1 enoyl CoA hydratase 1, peroxisomal 2.09908
ZYX zyxin 2.09844
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.09774
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.09091
ZNF155 zinc finger protein 155 2.08955
EXD3 exonuclease 3'-5' domain containing 3 2.08928
INO80B INO80 complex subunit B 2.08723
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.08639
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.0835
PLXNB1 plexin B1 2.08289
ATP10B ATPase, class V, type 10B 2.08285
LPA lipoprotein, Lp(a) 2.08148
SMC6 structural maintenance of chromosomes 6 2.08068
PLN phospholamban 2.07518
SARM1 sterile alpha and TIR motif containing 1 2.07383
LRRK1 leucine-rich repeat kinase 1 2.0726
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.07236
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.07228
RPL10A ribosomal protein L10a 2.07134
CIDEB cell death-inducing DFFA-like effector b 2.06811
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.068
MCC mutated in colorectal cancers 2.06795
JAG2 jagged 2 2.06171
NUAK1 NUAK family, SNF1-like kinase, 1 2.06092
FILIP1L filamin A interacting protein 1-like 2.06015
KLF11 Kruppel-like factor 11 2.05593
LALBA lactalbumin, alpha- 2.0557
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.05536
OLFML1 olfactomedin-like 1 2.05452
BTN3A3 butyrophilin, subfamily 3, member A3 2.05412
KEL Kell blood group, metallo-endopeptidase 2.05223
C2CD2 C2 calcium-dependent domain containing 2 2.05223
PLA2G2F phospholipase A2, group IIF 2.05221
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.0519
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.05067
FHL5 four and a half LIM domains 5 2.04893
USP36 ubiquitin specific peptidase 36 2.04874
PLXNB3 plexin B3 2.04522
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.04412
FBXW4 F-box and WD repeat domain containing 4 2.04323
KDM6B lysine (K)-specific demethylase 6B 2.04311
AMT aminomethyltransferase 2.04165
CBY1 chibby homolog 1 (Drosophila) 2.0412
TIMP2 TIMP metallopeptidase inhibitor 2 2.04028
PITPNB phosphatidylinositol transfer protein, beta 2.04026
PRR14L proline rich 14-like 2.03949
ITGA1 integrin, alpha 1 2.03811
SBF1 SET binding factor 1 2.0375
FMNL3 formin-like 3 2.03479
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 2.03371
TRIOBP TRIO and F-actin binding protein 2.02955
LRP5 low density lipoprotein receptor-related protein 5 2.02655
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.02606
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.02575
XDH xanthine dehydrogenase 2.02404
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.0229
KLF1 Kruppel-like factor 1 (erythroid) 2.02199
CAVIN1 caveolae associated protein 1 2.02156
TEK TEK tyrosine kinase, endothelial 2.02115
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.02092
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.01808
OLFML2A olfactomedin-like 2A 2.01769
ZNF665 zinc finger protein 665 2.01727
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.01596
METRN meteorin, glial cell differentiation regulator 2.01527
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.01523
YIPF3 Yip1 domain family, member 3 2.01397
ROGDI rogdi homolog (Drosophila) 2.01397
GPR137 G protein-coupled receptor 137 2.0139
SCGN secretagogin, EF-hand calcium binding protein 2.01299
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.01135
PLEK2 pleckstrin 2 2.01094
STX2 syntaxin 2 2.00924
DOK7 docking protein 7 2.0088
NAGLU N-acetylglucosaminidase, alpha 2.0065
USP27X ubiquitin specific peptidase 27, X-linked 2.00509
CUTA cutA divalent cation tolerance homolog (E. coli) 2.00469
ABHD14A abhydrolase domain containing 14A 2.00077
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.00014

decreased expression

Symbol Name Standardized Value
PLK1 polo-like kinase 1 -10.0
UBE2C ubiquitin-conjugating enzyme E2C -9.56156
CDC20 cell division cycle 20 -9.54631
KIF14 kinesin family member 14 -8.25037
KIF20A kinesin family member 20A -8.22909
CCNB2 cyclin B2 -7.89607
CCNA2 cyclin A2 -7.41444
PSRC1 proline/serine-rich coiled-coil 1 -7.16078
CDK1 cyclin-dependent kinase 1 -6.99226
GDF15 growth differentiation factor 15 -6.78286
BIRC5 baculoviral IAP repeat containing 5 -6.52154
TOP2A topoisomerase (DNA) II alpha 170kDa -6.45861
CBR3 carbonyl reductase 3 -6.26434
ADI1 acireductone dioxygenase 1 -5.72068
AURKA aurora kinase A -5.46398
CENPA centromere protein A -5.42495
DEPDC1 DEP domain containing 1 -5.06828
NEK2 NIMA-related kinase 2 -5.05328
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -5.0259
RPA3 replication protein A3, 14kDa -4.86126
CDCA3 cell division cycle associated 3 -4.80658
KIF4A kinesin family member 4A -4.64501
LBR lamin B receptor -4.61879
SPAG5 sperm associated antigen 5 -4.55131
OIP5 Opa interacting protein 5 -4.44153
GTF2A2 general transcription factor IIA, 2, 12kDa -4.42221
STMN1 stathmin 1 -4.40895
TPX2 TPX2, microtubule-associated -4.40718
CCNB1 cyclin B1 -4.39835
CDKN3 cyclin-dependent kinase inhibitor 3 -4.39782
FOXM1 forkhead box M1 -4.37529
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.36331
NLRP2B NLR family pyrin domain containing 2B -4.22073
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.21875
PBK PDZ binding kinase -4.15876
SLC35B1 solute carrier family 35, member B1 -4.14252
HJURP Holliday junction recognition protein -4.0583
NUSAP1 nucleolar and spindle associated protein 1 -4.01264
AURKB aurora kinase B -4.0011
TTK TTK protein kinase -3.99784
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.99195
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.97227
PIMREG PICALM interacting mitotic regulator -3.88263
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.88052
CD320 CD320 molecule -3.87562
GOLT1B golgi transport 1B -3.80859
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.78662
NCAPH non-SMC condensin I complex, subunit H -3.77696
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.75678
PCCB propionyl CoA carboxylase, beta polypeptide -3.74603
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.70034
CEP55 centrosomal protein 55kDa -3.68327
PRC1 protein regulator of cytokinesis 1 -3.67822
KIF23 kinesin family member 23 -3.66713
NCAPG2 non-SMC condensin II complex, subunit G2 -3.63909
CCNF cyclin F -3.6367
SPC25 SPC25, NDC80 kinetochore complex component -3.58786
RACGAP1 Rac GTPase activating protein 1 -3.54129
S100A4 S100 calcium binding protein A4 -3.52556
DDIT4 DNA-damage-inducible transcript 4 -3.48341
KIF11 kinesin family member 11 -3.47607
NCAPD2 non-SMC condensin I complex, subunit D2 -3.46849
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.45781
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.45602
TACC3 transforming, acidic coiled-coil containing protein 3 -3.40761
PARPBP PARP1 binding protein -3.40275
KIF18A kinesin family member 18A -3.38075
SPDL1 spindle apparatus coiled-coil protein 1 -3.37724
SHCBP1 SHC SH2-domain binding protein 1 -3.36787
DCK deoxycytidine kinase -3.34684
RPL39L ribosomal protein L39-like -3.33487
CDPF1 cysteine-rich, DPF motif domain containing 1 -3.31547
TROAP trophinin associated protein -3.31283
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -3.31152
TMEM267 transmembrane protein 267 -3.30225
EXOSC8 exosome component 8 -3.29428
ASF1B anti-silencing function 1B histone chaperone -3.28002
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -3.21358
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.18052
CDCA8 cell division cycle associated 8 -3.17674
BORA bora, aurora kinase A activator -3.1692
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.16285
COQ3 coenzyme Q3 methyltransferase -3.15061
CGRRF1 cell growth regulator with ring finger domain 1 -3.14993
ZWILCH zwilch kinetochore protein -3.14834
KIF18B kinesin family member 18B -3.12692
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.12454
CDC25C cell division cycle 25C -3.11871
LOC112694756 uncharaterized LOC112694756 -3.11635
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.11555
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.09273
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.06785
MSMO1 methylsterol monooxygenase 1 -3.05527
TRIB3 tribbles pseudokinase 3 -3.03069
HMGB2 high mobility group box 2 -3.02775
CCNC cyclin C -2.98324
PARP2 poly (ADP-ribose) polymerase 2 -2.98112
CEP70 centrosomal protein 70kDa -2.97838
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.96264
DBF4 DBF4 zinc finger -2.9576
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.95685
SLIRP SRA stem-loop interacting RNA binding protein -2.9462
ECT2 epithelial cell transforming 2 -2.94019
MARCHF5 membrane associated ring-CH-type finger 5 -2.92745
BASP1 brain abundant, membrane attached signal protein 1 -2.92504
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.89953
TRIP13 thyroid hormone receptor interactor 13 -2.88995
ACOT9 acyl-CoA thioesterase 9 -2.88898
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.8886
CKS1B CDC28 protein kinase regulatory subunit 1B -2.88459
ETV1 ets variant 1 -2.83858
TLK2 tousled-like kinase 2 -2.82786
MKI67 marker of proliferation Ki-67 -2.82681
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.82515
PALS1 protein associated with LIN7 1, MAGUK p55 family member -2.82152
TK1 thymidine kinase 1, soluble -2.80586
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.8039
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.80247
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.7799
NDC80 NDC80 kinetochore complex component -2.77897
MTMR2 myotubularin related protein 2 -2.76409
HOXA5 homeobox A5 -2.73572
SLC25A46 solute carrier family 25, member 46 -2.72692
ARID4B AT rich interactive domain 4B (RBP1-like) -2.70964
CETN3 centrin, EF-hand protein, 3 -2.7076
HAT1 histone acetyltransferase 1 -2.70354
TMPO thymopoietin -2.69434
CKAP2 cytoskeleton associated protein 2 -2.67996
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.66167
RPP30 ribonuclease P/MRP 30kDa subunit -2.63608
KCTD9 potassium channel tetramerization domain containing 9 -2.63012
RNASE7 ribonuclease, RNase A family, 7 -2.62872
CDC6 cell division cycle 6 -2.62029
PLK4 polo-like kinase 4 -2.61086
CKS2 CDC28 protein kinase regulatory subunit 2 -2.60521
TMCO1 transmembrane and coiled-coil domains 1 -2.59373
DCP2 decapping mRNA 2 -2.58405
SMC4 structural maintenance of chromosomes 4 -2.58293
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.57456
CENPN centromere protein N -2.56753
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.55731
MED21 mediator complex subunit 21 -2.55574
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.55265
APOO apolipoprotein O -2.55034
UBE2S ubiquitin-conjugating enzyme E2S -2.54674
KIF22 kinesin family member 22 -2.54348
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid -2.54289
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -2.52589
GTPBP8 GTP-binding protein 8 (putative) -2.52541
LOC128966597 MAL-like protein -2.52453
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.51831
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.51407
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.50614
GRAMD1B GRAM domain containing 1B -2.50224
SKA1 spindle and kinetochore associated complex subunit 1 -2.48754
USP39 ubiquitin specific peptidase 39 -2.47623
PRDX4 peroxiredoxin 4 -2.47449
ZWINT ZW10 interacting kinetochore protein -2.47197
CKAP5 cytoskeleton associated protein 5 -2.47123
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.47082
LDHD lactate dehydrogenase D -2.46833
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.46448
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.45175
SRBD1 S1 RNA binding domain 1 -2.44985
KLHL7 kelch-like family member 7 -2.44316
GIN1 gypsy retrotransposon integrase 1 -2.44269
FER fer (fps/fes related) tyrosine kinase -2.42974
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.42713
GPN3 GPN-loop GTPase 3 -2.42108
TCERG1 transcription elongation regulator 1 -2.41555
CEP76 centrosomal protein 76kDa -2.41328
CHI3L2 chitinase 3-like 2 -2.41104
RRM1 ribonucleotide reductase M1 -2.40785
TP53RK TP53 regulating kinase -2.40384
ATP5MF ATP synthase membrane subunit f -2.39001
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.38928
PTTG1 pituitary tumor-transforming 1 -2.38531
OXSR1 oxidative stress responsive 1 -2.37474
PGAM4 phosphoglycerate mutase family member 4 -2.37189
YME1L1 YME1-like 1 ATPase -2.36396
KDM3A lysine (K)-specific demethylase 3A -2.36329
NUP155 nucleoporin 155kDa -2.3615
SRPRB signal recognition particle receptor, B subunit -2.35964
MFN1 mitofusin 1 -2.35152
ZNF143 zinc finger protein 143 -2.34967
RAB5IF RAB5 interacting factor -2.33815
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.33271
INSIG1 insulin induced gene 1 -2.32636
SERP1 stress-associated endoplasmic reticulum protein 1 -2.321
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.29828
NCAPG non-SMC condensin I complex, subunit G -2.29752
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.2952
ECD ecdysoneless homolog (Drosophila) -2.29421
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.28867
NCBP2 nuclear cap binding protein subunit 2, 20kDa -2.28128
FAIM Fas apoptotic inhibitory molecule -2.27886
BLTP3B bridge-like lipid transfer protein family member 3B -2.27492
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -2.27366
MTMR6 myotubularin related protein 6 -2.26603
CLTC clathrin, heavy chain (Hc) -2.26494
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -2.26026
RPAP3 RNA polymerase II associated protein 3 -2.25907
SELL selectin L -2.24753
PAIP1 poly(A) binding protein interacting protein 1 -2.24465
BLMH bleomycin hydrolase -2.23752
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.23739
BRIX1 BRX1, biogenesis of ribosomes -2.23446
KIF2C kinesin family member 2C -2.23208
RFC3 replication factor C (activator 1) 3, 38kDa -2.22777
SBNO1 strawberry notch homolog 1 (Drosophila) -2.2246
CDC23 cell division cycle 23 -2.22379
SEC61B Sec61 beta subunit -2.21525
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.21476
NT5C2 5'-nucleotidase, cytosolic II -2.21236
ACAA1 acetyl-CoA acyltransferase 1 -2.20364
CYCS cytochrome c, somatic -2.19762
SLC25A40 solute carrier family 25, member 40 -2.19257
SESN1 sestrin 1 -2.19136
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.1888
ASF1A anti-silencing function 1A histone chaperone -2.18736
DBR1 debranching RNA lariats 1 -2.18399
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough -2.18009
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.17896
MCM10 minichromosome maintenance complex component 10 -2.17487
KIFC1 kinesin family member C1 -2.17094
LOC128125822 uncharacterized LOC128125822 -2.169
ERCC6L excision repair cross-complementation group 6-like -2.16234
ANXA7 annexin A7 -2.1586
AQP4 aquaporin 4 -2.15721
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.15213
TIMP1 TIMP metallopeptidase inhibitor 1 -2.15176
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -2.14599
IDE insulin-degrading enzyme -2.13701
GMNN geminin, DNA replication inhibitor -2.13652
FASTKD3 FAST kinase domains 3 -2.13596
SPA17 sperm autoantigenic protein 17 -2.13425
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.13414
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.13349
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.13339
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.13084
ARGLU1 arginine and glutamate rich 1 -2.13073
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.12724
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.12061
PHGDH phosphoglycerate dehydrogenase -2.11592
CASC3 cancer susceptibility candidate 3 -2.11218
ARHGAP19 Rho GTPase activating protein 19 -2.10215
ZNF226 zinc finger protein 226 -2.10046
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.09231
IL13RA2 interleukin 13 receptor, alpha 2 -2.09007
JPT1 Jupiter microtubule associated homolog 1 -2.08698
TEFM transcription elongation factor, mitochondrial -2.08664
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.08557
PCDHB16 protocadherin beta 16 -2.08503
CEP43 centrosomal protein 43 -2.08274
MRPS16 mitochondrial ribosomal protein S16 -2.07524
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.07212
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.07082
S100A2 S100 calcium binding protein A2 -2.06967
GOLGA7 golgin A7 -2.06732
PROSER1 proline and serine rich 1 -2.06571
TSPYL5 TSPY-like 5 -2.06552
NPR2 natriuretic peptide receptor 2 -2.06216
KIF20B kinesin family member 20B -2.06179
TFG TRK-fused gene -2.06035
THAP11 THAP domain containing 11 -2.05837
PRR15L proline rich 15-like -2.05728
RFC4 replication factor C (activator 1) 4, 37kDa -2.05693
TECR trans-2,3-enoyl-CoA reductase -2.0513
H2AZ1 H2A.Z variant histone 1 -2.05019
GPN1 GPN-loop GTPase 1 -2.0451
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -2.04501
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.04296
MRPL44 mitochondrial ribosomal protein L44 -2.03958
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.03535
CENPC centromere protein C -2.03394
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.03284
CAB39 calcium binding protein 39 -2.03245
BCCIP BRCA2 and CDKN1A interacting protein -2.0319
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.02375
TBPL1 TBP-like 1 -2.02157
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.02121
ZNF211 zinc finger protein 211 -2.02019
KIF15 kinesin family member 15 -2.01999
DCLRE1A DNA cross-link repair 1A -2.01508
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.01467
NMI N-myc (and STAT) interactor -2.01364
ZNF528 zinc finger protein 528 -2.00718
POT1 protection of telomeres 1 -2.00685
SNRPG small nuclear ribonucleoprotein polypeptide G -2.00497
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.00205