CRCGN016_MCF10A.WT.HP_24H:K14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dibromo-3-chloropropane 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.99864
OLFML2B olfactomedin-like 2B 3.95095
MTA2 metastasis associated 1 family, member 2 3.0063
FBXL12 F-box and leucine-rich repeat protein 12 2.90544
NUTF2 nuclear transport factor 2 2.48346
COQ8A coenzyme Q8A 2.32381
COMP cartilage oligomeric matrix protein 2.18999
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.1759
BRCA1 breast cancer 1, early onset 2.1649
RBBP5 retinoblastoma binding protein 5 2.13605
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.01251

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -8.09306
GDF15 growth differentiation factor 15 -5.39093
HMG20B high mobility group 20B -4.44475
RNF167 ring finger protein 167 -4.28181
CANT1 calcium activated nucleotidase 1 -3.55742
BID BH3 interacting domain death agonist -3.37158
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.07623
SGK1 serum/glucocorticoid regulated kinase 1 -2.71633