CRCGN016_MCF10A.WT.HP_24H:K17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetaldehyde 34.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.93972
FKBP14 FK506 binding protein 14, 22 kDa 4.45525
SPAG4 sperm associated antigen 4 3.85237
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.68848
HBA1 hemoglobin, alpha 1 3.40072
ADGRE5 adhesion G protein-coupled receptor E5 3.37711
ACAA1 acetyl-CoA acyltransferase 1 3.16806
AGR2 anterior gradient 2 3.04916
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.95979
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.59583
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 2.35151
TMEM255A transmembrane protein 255A 2.28534
MYBPC3 myosin binding protein C, cardiac 2.21022
PPA1 pyrophosphatase (inorganic) 1 2.11916
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.09881
LOC102724023 ES1 protein homolog, mitochondrial 2.08354
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 2.08268
CRELD2 cysteine-rich with EGF-like domains 2 2.05679
ALPK1 alpha-kinase 1 2.04942
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.04753
MTUS2 microtubule associated tumor suppressor candidate 2 2.04684
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.01954
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.01031

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -5.38001
TSPAN4 tetraspanin 4 -5.04925
PCCB propionyl CoA carboxylase, beta polypeptide -4.51872
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.4701
DERA deoxyribose-phosphate aldolase (putative) -4.33587
KIF20A kinesin family member 20A -2.94086
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.80242
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.61201
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.59431
TENT4A terminal nucleotidyltransferase 4A -2.27948
TES testin LIM domain protein -2.17242
KRT14 keratin 14, type I -2.09979
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.08525
WDR26 WD repeat domain 26 -2.01149