CRCGN016_MCF10A.WT.HP_24H:K18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetaldehyde 11.53 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSPAN6 tetraspanin 6 3.35183
PRR7 proline rich 7 (synaptic) 3.34463
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.87835
PMF1-BGLAP PMF1-BGLAP readthrough 2.28468
SATB1 SATB homeobox 1 2.26044
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.2231
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.2008
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.16946
NUCB2 nucleobindin 2 2.15061
HMG20B high mobility group 20B 2.07472
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.07009
PCNT pericentrin 2.04601
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.04039
CHN1 chimerin 1 2.02436

decreased expression

Symbol Name Standardized Value
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.37941
TIMP1 TIMP metallopeptidase inhibitor 1 -3.99703
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.18343
MSMO1 methylsterol monooxygenase 1 -3.11366
SMNDC1 survival motor neuron domain containing 1 -3.06451
TOMM34 translocase of outer mitochondrial membrane 34 -2.85105
RPN1 ribophorin I -2.77742
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.63361
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.54952
BID BH3 interacting domain death agonist -2.54269
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.51603
NUP93 nucleoporin 93kDa -2.37598
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.31715
TXNRD1 thioredoxin reductase 1 -2.29939
BAG3 BCL2-associated athanogene 3 -2.21877
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.18959
PRSS3 protease, serine, 3 -2.15769
EXOSC4 exosome component 4 -2.15103
TBPL1 TBP-like 1 -2.07927
UFM1 ubiquitin-fold modifier 1 -2.06651
MAT2A methionine adenosyltransferase II, alpha -2.01575
RPA3 replication protein A3, 14kDa -2.00492