CRCGN016_MCF10A.WT.HP_24H:K21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cresol 11.08 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.74799
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.55353
CXCR4 chemokine (C-X-C motif) receptor 4 4.03705
AGR2 anterior gradient 2 3.69257
KCTD5 potassium channel tetramerization domain containing 5 3.52839
CCL2 chemokine (C-C motif) ligand 2 3.42389
ZBTB35 zinc finger and BTB domain containing 35 2.42687
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.15956

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -4.71462
BASP1 brain abundant, membrane attached signal protein 1 -4.25477
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -4.23137
CCDC86 coiled-coil domain containing 86 -4.10678
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.04781
NRIP1 nuclear receptor interacting protein 1 -3.01406
CLTB clathrin, light chain B -2.98716
SOAT2 sterol O-acyltransferase 2 -2.62531
TCEA2 transcription elongation factor A (SII), 2 -2.43738
COPS6 COP9 signalosome subunit 6 -2.15576
KRT14 keratin 14, type I -2.12513
GK glycerol kinase -2.00363