CRCGN016_MCF10A.WT.HP_24H:L01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sorbic-acid 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.2632
HBA1 hemoglobin, alpha 1 3.38197
PDGFA platelet-derived growth factor alpha polypeptide 3.32435
RSF1 remodeling and spacing factor 1 2.76424
PKN1 protein kinase N1 2.54876
RAB31 RAB31, member RAS oncogene family 2.3492
AAMDC adipogenesis associated, Mth938 domain containing 2.27625
CHMP1A charged multivesicular body protein 1A 2.12014
RAB21 RAB21, member RAS oncogene family 2.06735
INTS9 integrator complex subunit 9 2.05693
DENND2D DENN/MADD domain containing 2D 2.02649
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.0244
EIF3G eukaryotic translation initiation factor 3, subunit G 2.00905

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.61467
TSPAN4 tetraspanin 4 -4.4274
DNM1L dynamin 1-like -4.21599
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -4.12659
KRT14 keratin 14, type I -3.49922
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.32219
AURKB aurora kinase B -3.15986
CAPRIN2 caprin family member 2 -3.03872
EXOSC4 exosome component 4 -3.00058
NVL nuclear VCP-like -2.80098
ERGIC2 ERGIC and golgi 2 -2.63656
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -2.57808
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.52053
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.40406
ACAA1 acetyl-CoA acyltransferase 1 -2.3214
SINHCAF SIN3-HDAC complex associated factor -2.2238
EFNA3 ephrin-A3 -2.16153
GDF15 growth differentiation factor 15 -2.14319
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.10141
SLC35F6 solute carrier family 35, member F6 -2.08726
AVL9 AVL9 homolog (S. cerevisiase) -2.06056
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -2.03782
MINDY3 MINDY lysine 48 deubiquitinase 3 -2.00557