CRCGN016_MCF10A.WT.HP_24H:L03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sorbic-acid 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LAGE3 L antigen family, member 3 3.30239
MAMLD1 mastermind-like domain containing 1 2.8172
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.67819
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.29113
GPER1 G protein-coupled estrogen receptor 1 2.27966
TXLNA taxilin alpha 2.12848
TRAK2 trafficking protein, kinesin binding 2 2.06084
CNPY3 canopy FGF signaling regulator 3 2.00812

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.64558
GADD45B growth arrest and DNA-damage-inducible, beta -4.2027
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.81201
DSG2 desmoglein 2 -3.27509
PCNA proliferating cell nuclear antigen -3.15613
REEP5 receptor accessory protein 5 -2.83324
ANXA2 annexin A2 -2.70713
RXYLT1 ribitol xylosyltransferase 1 -2.6396
VDAC1 voltage-dependent anion channel 1 -2.56543
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.27603
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.26378