CRCGN016_MCF10A.WT.HP_24H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hydrazine sulfate 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 4.43376
C2CD2 C2 calcium-dependent domain containing 2 4.30687
EPN2 epsin 2 3.62928
KLHL9 kelch-like family member 9 3.477
BAX BCL2-associated X protein 2.95604
FOCAD focadhesin 2.11036

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -4.54932
CDK4 cyclin-dependent kinase 4 -4.12589
ACAA1 acetyl-CoA acyltransferase 1 -2.52365
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -2.46977
MTERF3 mitochondrial transcription termination factor 3 -2.33649
HTRA1 HtrA serine peptidase 1 -2.16247
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.14218
TSFM Ts translation elongation factor, mitochondrial -2.10522
CRTAM cytotoxic and regulatory T cell molecule -2.03244
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.02563