CRCGN016_MCF10A.WT.HP_24H:L09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description fd & c blue no. 2 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.02183
CDCA4 cell division cycle associated 4 2.98371
WFS1 Wolfram syndrome 1 (wolframin) 2.52151
KIF5C kinesin family member 5C 2.31069
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.09847
STK10 serine/threonine kinase 10 2.07677

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.79602
HMG20B high mobility group 20B -4.21407
TXNDC9 thioredoxin domain containing 9 -3.77497
SNCA synuclein, alpha (non A4 component of amyloid precursor) -3.63819
ADI1 acireductone dioxygenase 1 -3.40491
CCNB1 cyclin B1 -3.3593
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.24641
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.23518
BASP1 brain abundant, membrane attached signal protein 1 -2.93188
YME1L1 YME1-like 1 ATPase -2.80258
ISOC1 isochorismatase domain containing 1 -2.26138
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.12944