CRCGN016_MCF10A.WT.HP_24H:L10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description disulfiram 99.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

896 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GADD45B growth arrest and DNA-damage-inducible, beta 10.0
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 10.0
CEMIP2 cell migration inducing hyaluronidase 2 10.0
FOS FBJ murine osteosarcoma viral oncogene homolog 9.3371
HSPA1A heat shock 70kDa protein 1A 9.06544
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 8.59673
RGS2 regulator of G-protein signaling 2 8.37225
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 8.29688
CXCL2 chemokine (C-X-C motif) ligand 2 7.77725
TRIB1 tribbles pseudokinase 1 7.67981
HMOX1 heme oxygenase 1 7.63369
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 7.26609
HSPA1B heat shock 70kDa protein 1B 6.4235
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 6.40752
WIF1 WNT inhibitory factor 1 6.10424
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.87162
NUP93 nucleoporin 93kDa 5.86004
CADM1 cell adhesion molecule 1 5.7706
MMP1 matrix metallopeptidase 1 5.74996
ALAS1 5'-aminolevulinate synthase 1 5.7454
PPP1R15A protein phosphatase 1, regulatory subunit 15A 5.71258
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 5.57008
NUCB2 nucleobindin 2 5.52294
IGFBP3 insulin-like growth factor binding protein 3 5.38106
COMP cartilage oligomeric matrix protein 5.36427
HSPA6 heat shock 70kDa protein 6 (HSP70B') 5.17281
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5.07615
EGR1 early growth response 1 4.94526
BAG3 BCL2-associated athanogene 3 4.89865
BAMBI BMP and activin membrane-bound inhibitor 4.82353
AGR2 anterior gradient 2 4.8233
IL1B interleukin 1, beta 4.75944
COL4A1 collagen, type IV, alpha 1 4.75298
H2BC12 H2B clustered histone 12 4.73247
FHL2 four and a half LIM domains 2 4.723
ABHD4 abhydrolase domain containing 4 4.64302
SLC35B1 solute carrier family 35, member B1 4.60822
SQSTM1 sequestosome 1 4.42802
IER5 immediate early response 5 4.40221
ADRB2 adrenoceptor beta 2, surface 4.36864
MYL9 myosin, light chain 9, regulatory 4.32542
WFS1 Wolfram syndrome 1 (wolframin) 4.29479
GPER1 G protein-coupled estrogen receptor 1 4.21307
IFRD1 interferon-related developmental regulator 1 4.18741
CHIC2 cysteine-rich hydrophobic domain 2 4.16749
H2BC9 H2B clustered histone 9 4.16174
TBPL1 TBP-like 1 4.11608
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.01907
FOSB FBJ murine osteosarcoma viral oncogene homolog B 4.00839
IER2 immediate early response 2 3.97983
LIN37 lin-37 DREAM MuvB core complex component 3.93415
ADRM1 adhesion regulating molecule 1 3.89145
H2BC4 H2B clustered histone 4 3.87625
ISG20 interferon stimulated exonuclease gene 20kDa 3.8585
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.84977
RMC1 regulator of MON1-CCZ1 3.82591
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.80885
SART1 squamous cell carcinoma antigen recognized by T cells 3.78238
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.71956
JMJD6 jumonji domain containing 6 3.71761
RHOB ras homolog family member B 3.57649
PPY pancreatic polypeptide 3.57423
RGS16 regulator of G-protein signaling 16 3.5584
SNAP25 synaptosomal-associated protein, 25kDa 3.52991
GADD45A growth arrest and DNA-damage-inducible, alpha 3.52947
MSX2 msh homeobox 2 3.52173
ATF3 activating transcription factor 3 3.48012
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 3.45899
LGMN legumain 3.4502
H2AC7 H2A clustered histone 7 3.43723
CXCL3 chemokine (C-X-C motif) ligand 3 3.39705
RND1 Rho family GTPase 1 3.39446
H2BC3 H2B clustered histone 3 3.38601
ATG101 autophagy related 101 3.37099
GADD45G growth arrest and DNA-damage-inducible, gamma 3.33771
CCL3L3 chemokine (C-C motif) ligand 3-like 3 3.33663
JUN jun proto-oncogene 3.33013
H2AC19 H2A clustered histone 19 3.31279
SMIM40 small integral membrane protein 40 3.27495
CTSL cathepsin L 3.27093
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.25827
RNASE7 ribonuclease, RNase A family, 7 3.24966
ADM adrenomedullin 3.24671
ACAA1 acetyl-CoA acyltransferase 1 3.22787
IRF7 interferon regulatory factor 7 3.22323
H1-2 H1.2 linker histone, cluster member 3.16054
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.15167
STX5 syntaxin 5 3.14533
CTNNBL1 catenin, beta like 1 3.14167
EDN1 endothelin 1 3.13165
ZBED2 zinc finger, BED-type containing 2 3.10436
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 3.09726
AEBP1 AE binding protein 1 3.07572
TUFT1 tuftelin 1 3.07139
LOC128125814 uncharacterized LOC128125814 3.06206
CDKN2AIP CDKN2A interacting protein 3.04836
DUSP14 dual specificity phosphatase 14 3.04799
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.04537
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.04191
MOK MOK protein kinase 3.03669
INHBA inhibin, beta A 3.00401
DLX5 distal-less homeobox 5 2.99152
UGDH UDP-glucose 6-dehydrogenase 2.97451
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 2.96531
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.96486
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.96278
RBM22 RNA binding motif protein 22 2.95284
UFD1 ubiquitin recognition factor in ER associated degradation 1 2.94458
SMIM29 small integral membrane protein 29 2.93764
MRPL18 mitochondrial ribosomal protein L18 2.9248
TMEM40 transmembrane protein 40 2.9209
TUBB6 tubulin, beta 6 class V 2.91745
HYOU1 hypoxia up-regulated 1 2.90785
CSRP2 cysteine and glycine-rich protein 2 2.90368
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.89435
H2AC4 H2A clustered histone 4 2.88665
KRT8 keratin 8, type II 2.88186
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.87219
DEPP1 DEPP autophagy regulator 1 2.83982
ALDOC aldolase C, fructose-bisphosphate 2.8318
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.82785
DLX2 distal-less homeobox 2 2.81701
MACO1 macoilin 1 2.81373
BRMS1L breast cancer metastasis-suppressor 1-like 2.8044
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.80283
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.79439
TUBB2A tubulin, beta 2A class IIa 2.77571
NUDC nudC nuclear distribution protein 2.76663
RBM6 RNA binding motif protein 6 2.74853
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.74334
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.73437
EN2 engrailed homeobox 2 2.73288
HSPA2 heat shock 70kDa protein 2 2.72337
PDPN podoplanin 2.70961
RTF2 replication termination factor 2 2.70152
NUAK1 NUAK family, SNF1-like kinase, 1 2.69143
MT1M metallothionein 1M 2.6874
CYTH2 cytohesin 2 2.68688
ADGRE5 adhesion G protein-coupled receptor E5 2.68548
REXO5 RNA exonuclease 5 2.68507
HDAC9 histone deacetylase 9 2.67847
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.67827
PLIN2 perilipin 2 2.66565
TNIP1 TNFAIP3 interacting protein 1 2.6638
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.65567
TIMP2 TIMP metallopeptidase inhibitor 2 2.65199
BTG1 B-cell translocation gene 1, anti-proliferative 2.64847
FRS2 fibroblast growth factor receptor substrate 2 2.64782
TTLL7 tubulin tyrosine ligase-like family member 7 2.64753
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.64595
STX4 syntaxin 4 2.63713
ENTREP1 endosomal transmembrane epsin interactor 1 2.63234
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.62943
RNF25 ring finger protein 25 2.62462
STIP1 stress-induced phosphoprotein 1 2.61872
GBX2 gastrulation brain homeobox 2 2.61136
SNAI1 snail family zinc finger 1 2.60383
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.57924
NOSIP nitric oxide synthase interacting protein 2.57238
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 2.56903
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.56074
ZFPM1 zinc finger protein, FOG family member 1 2.55143
CAVIN3 caveolae associated protein 3 2.549
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.54464
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.54334
NUPR1 nuclear protein, transcriptional regulator, 1 2.5426
TPM1 tropomyosin 1 (alpha) 2.54112
LAP3 leucine aminopeptidase 3 2.53822
MED17 mediator complex subunit 17 2.53062
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.52818
FGF3 fibroblast growth factor 3 2.52293
VWF von Willebrand factor 2.51666
HYI hydroxypyruvate isomerase (putative) 2.51573
CORO1A coronin, actin binding protein, 1A 2.51494
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.51019
ELOVL1 ELOVL fatty acid elongase 1 2.5033
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.50246
RAB30 RAB30, member RAS oncogene family 2.49546
MICB MHC class I polypeptide-related sequence B 2.48879
PSEN2 presenilin 2 2.48451
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.47691
KRT34 keratin 34, type I 2.47341
MSMB microseminoprotein, beta- 2.4709
UBQLN2 ubiquilin 2 2.46366
PSPC1 paraspeckle component 1 2.46086
AMIGO2 adhesion molecule with Ig-like domain 2 2.45589
MMP11 matrix metallopeptidase 11 2.44812
AGER advanced glycosylation end product-specific receptor 2.44748
BUD31 BUD31 homolog (S. cerevisiae) 2.42297
IRS1 insulin receptor substrate 1 2.4212
FRMD4B FERM domain containing 4B 2.41535
TSPAN13 tetraspanin 13 2.41493
RNF103 ring finger protein 103 2.41112
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.41038
GATA2 GATA binding protein 2 2.40871
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.40786
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.40388
TSPAN7 tetraspanin 7 2.39909
TMSB15B thymosin beta 15B 2.39308
SYNC syncoilin, intermediate filament protein 2.38856
ANGPT2 angiopoietin 2 2.38726
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.38659
KANK3 KN motif and ankyrin repeat domains 3 2.37877
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.37627
MMP9 matrix metallopeptidase 9 2.37522
CDK11A cyclin-dependent kinase 11A 2.37075
STK10 serine/threonine kinase 10 2.36355
ERCC1 excision repair cross-complementation group 1 2.36165
CCNE2 cyclin E2 2.36163
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.36072
APLNR apelin receptor 2.35641
NANS N-acetylneuraminic acid synthase 2.35473
GDI1 GDP dissociation inhibitor 1 2.35197
ALOXE3 arachidonate lipoxygenase 3 2.3507
LOC102724023 ES1 protein homolog, mitochondrial 2.34779
HPGDS hematopoietic prostaglandin D synthase 2.34665
H2BC21 H2B clustered histone 21 2.34582
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.34551
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.34505
CLDN18 claudin 18 2.34249
APLP1 amyloid beta (A4) precursor-like protein 1 2.33732
CLTB clathrin, light chain B 2.33166
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.33116
SH2D2A SH2 domain containing 2A 2.32589
NT5E 5'-nucleotidase, ecto (CD73) 2.32483
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.32143
H4C15 H4 clustered histone 15 2.31728
HBEGF heparin-binding EGF-like growth factor 2.31548
RNFT1-DT RNFT1 divergent transcript 2.31394
TPO thyroid peroxidase 2.30703
CXCR4 chemokine (C-X-C motif) receptor 4 2.29973
ARID5B AT rich interactive domain 5B (MRF1-like) 2.2926
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.29089
MON1B MON1 secretory trafficking family member B 2.29062
ZDHHC14 zinc finger, DHHC-type containing 14 2.28431
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.28219
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.27975
EN1 engrailed homeobox 1 2.27825
THSD1 thrombospondin, type I, domain containing 1 2.27185
FN1 fibronectin 1 2.27036
ARG2 arginase 2 2.27032
SCT secretin 2.26397
RIOK3 RIO kinase 3 2.2633
COL8A2 collagen, type VIII, alpha 2 2.26107
VSTM4 V-set and transmembrane domain containing 4 2.25608
TFRC transferrin receptor 2.25381
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.25042
TMEM204 transmembrane protein 204 2.24977
SDC4 syndecan 4 2.24933
LRRC15 leucine rich repeat containing 15 2.24889
FAM107A family with sequence similarity 107, member A 2.24461
SPHK1 sphingosine kinase 1 2.24172
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 2.24004
FICD FIC domain containing 2.2392
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.23868
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.2379
AATF apoptosis antagonizing transcription factor 2.23743
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.23435
TBX3 T-box 3 2.23345
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.23317
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.22981
KLF6 Kruppel-like factor 6 2.22788
IL23A interleukin 23, alpha subunit p19 2.22768
CDC34 cell division cycle 34 2.22743
IGSF1 immunoglobulin superfamily, member 1 2.22536
H1-4 H1.4 linker histone, cluster member 2.22491
OSR2 odd-skipped related transciption factor 2 2.22464
HPSE heparanase 2.22229
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.22189
YOD1 YOD1 deubiquitinase 2.22073
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.21928
EHD1 EH-domain containing 1 2.21669
GPKOW G patch domain and KOW motifs 2.2152
NACAD NAC alpha domain containing 2.21508
RAB3B RAB3B, member RAS oncogene family 2.21269
JCAD junctional cadherin 5 associated 2.20866
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.20359
TFF2 trefoil factor 2 2.19958
CAVIN1 caveolae associated protein 1 2.19666
CLIC3 chloride intracellular channel 3 2.19588
ASCC2 activating signal cointegrator 1 complex subunit 2 2.19559
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.1932
RASL11B RAS-like, family 11, member B 2.18806
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.18691
THBS1 thrombospondin 1 2.18065
DENND2A DENN/MADD domain containing 2A 2.18019
ELMO1 engulfment and cell motility 1 2.17721
FGF20 fibroblast growth factor 20 2.17375
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.16474
MTSS1 metastasis suppressor 1 2.16376
HSPA8 heat shock 70kDa protein 8 2.16371
KATNA1 katanin p60 (ATPase containing) subunit A 1 2.16136
TBCB tubulin folding cofactor B 2.15968
CCND3 cyclin D3 2.15942
CIRSR corepressor of RBPJ and splicing regulator 2.15739
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.15711
LRP10 low density lipoprotein receptor-related protein 10 2.15622
ANGPTL2 angiopoietin-like 2 2.15416
INSM1 insulinoma-associated 1 2.1536
PXDC1 PX domain containing 1 2.15116
CCN2 cellular communication network factor 2 2.14887
ZNF586 zinc finger protein 586 2.14859
NBAS neuroblastoma amplified sequence 2.14661
ZNF304 zinc finger protein 304 2.1452
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.14475
TPST2 tyrosylprotein sulfotransferase 2 2.14109
ZNF34 zinc finger protein 34 2.14045
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.13982
IBSP integrin-binding sialoprotein 2.13977
TCP11L1 t-complex 11, testis-specific-like 1 2.13818
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.13747
ZC3H7A zinc finger CCCH-type containing 7A 2.13475
DDA1 DET1 and DDB1 associated 1 2.13445
CSF3 colony stimulating factor 3 (granulocyte) 2.13309
SMCO4 single-pass membrane protein with coiled-coil domains 4 2.13135
ZBTB10 zinc finger and BTB domain containing 10 2.13096
TUBA4B tubulin, alpha 4b 2.13002
PTK2B protein tyrosine kinase 2 beta 2.12889
IFI35 interferon-induced protein 35 2.12853
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.12759
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 2.12544
ZNF821 zinc finger protein 821 2.12247
ADORA2A adenosine A2a receptor 2.12231
MARCO macrophage receptor with collagenous structure 2.11895
GPX7 glutathione peroxidase 7 2.1153
KLF4 Kruppel-like factor 4 (gut) 2.11167
CD83 CD83 molecule 2.10849
H2BC5 H2B clustered histone 5 2.10808
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.10432
CEP131 centrosomal protein 131kDa 2.10344
SIRT7 sirtuin 7 2.10151
NGB neuroglobin 2.09644
EFNA1 ephrin-A1 2.0938
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.09325
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.09268
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.0918
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.09021
ZNF79 zinc finger protein 79 2.08041
FBXL12 F-box and leucine-rich repeat protein 12 2.07835
SEC14L1 SEC14-like 1 (S. cerevisiae) 2.07388
COL4A2 collagen, type IV, alpha 2 2.07016
PMP22 peripheral myelin protein 22 2.06916
IL6 interleukin 6 2.06876
CCNL1 cyclin L1 2.06791
MYH9 myosin, heavy chain 9, non-muscle 2.06644
GOLT1B golgi transport 1B 2.0663
H3C7 H3 clustered histone 7 2.06413
ARC activity-regulated cytoskeleton-associated protein 2.06338
KLF11 Kruppel-like factor 11 2.06065
UBXN1 UBX domain protein 1 2.05987
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.05947
PLA2G15 phospholipase A2, group XV 2.05791
COCH cochlin 2.05493
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 2.05317
GLRX2 glutaredoxin 2 2.05278
RGCC regulator of cell cycle 2.05277
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.05231
BMP4 bone morphogenetic protein 4 2.05146
GC group-specific component (vitamin D binding protein) 2.05057
YEATS2 YEATS domain containing 2 2.04996
LGALS4 lectin, galactoside-binding, soluble, 4 2.04984
SLC38A12 solute carrier family 38 member 12 2.04918
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.04895
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.0487
LOC127933115 uncharacterized LOC127933115 2.04729
ZBTB17 zinc finger and BTB domain containing 17 2.04645
CD38 CD38 molecule 2.04436
HHEX hematopoietically expressed homeobox 2.03889
FOXF2 forkhead box F2 2.0383
IER3 immediate early response 3 2.03606
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.03455
PDCL3 phosducin-like 3 2.03419
CRISP3 cysteine-rich secretory protein 3 2.03107
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.02629
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.02539
CYB5R3 cytochrome b5 reductase 3 2.02526
ISG15 ISG15 ubiquitin-like modifier 2.02424
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2.02186
IFI6 interferon, alpha-inducible protein 6 2.01988
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.01984
TCEAL2 transcription elongation factor A (SII)-like 2 2.01564
MMP10 matrix metallopeptidase 10 2.01486
CLDN5 claudin 5 2.01347
ZNF155 zinc finger protein 155 2.01149
PTGDR2 prostaglandin D2 receptor 2 2.00963
CTSB cathepsin B 2.00907
CSRNP2 cysteine-serine-rich nuclear protein 2 2.00763
CBLN1 cerebellin 1 precursor 2.00751
KRT5 keratin 5, type II 2.00688
GABPB1 GA binding protein transcription factor, beta subunit 1 2.00286
HTRA1 HtrA serine peptidase 1 2.00083

decreased expression

Symbol Name Standardized Value
DDIT4 DNA-damage-inducible transcript 4 -7.98457
MSMO1 methylsterol monooxygenase 1 -7.78365
PCCB propionyl CoA carboxylase, beta polypeptide -6.57217
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.50125
CPNE3 copine III -6.0879
ADI1 acireductone dioxygenase 1 -5.38548
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.25881
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.07026
COG2 component of oligomeric golgi complex 2 -4.93511
TOP2A topoisomerase (DNA) II alpha 170kDa -4.82229
CRTAP cartilage associated protein -4.7695
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.73908
PRCP prolylcarboxypeptidase (angiotensinase C) -4.73329
SREBF1 sterol regulatory element binding transcription factor 1 -4.73282
CD58 CD58 molecule -4.73253
PGAM4 phosphoglycerate mutase family member 4 -4.72125
LDHD lactate dehydrogenase D -4.62558
TSPAN6 tetraspanin 6 -4.61381
NISCH nischarin -4.54082
SESN1 sestrin 1 -4.43569
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.37056
PLS1 plastin 1 -4.27664
EXTL2 exostosin-like glycosyltransferase 2 -4.27031
RPA3 replication protein A3, 14kDa -4.26355
INSIG1 insulin induced gene 1 -4.26119
PGM1 phosphoglucomutase 1 -4.17203
TRAP1 TNF receptor-associated protein 1 -4.03542
HOXA5 homeobox A5 -3.99764
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.88763
KHDC4 KH domain containing 4, pre-mRNA splicing factor -3.88459
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.8584
TMEM267 transmembrane protein 267 -3.85772
HADH hydroxyacyl-CoA dehydrogenase -3.854
CISD1 CDGSH iron sulfur domain 1 -3.83997
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -3.8379
GTPBP8 GTP-binding protein 8 (putative) -3.83752
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.81585
ZNF451 zinc finger protein 451 -3.70996
ATMIN ATM interactor -3.69675
OXA1L oxidase (cytochrome c) assembly 1-like -3.66955
C1QBP complement component 1, q subcomponent binding protein -3.65593
AP3M2 adaptor-related protein complex 3, mu 2 subunit -3.62159
PHKB phosphorylase kinase, beta -3.60527
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.60043
GTF2A2 general transcription factor IIA, 2, 12kDa -3.58275
HEATR1 HEAT repeat containing 1 -3.56079
PPA2 pyrophosphatase (inorganic) 2 -3.54638
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.51289
C2CD5 C2 calcium-dependent domain containing 5 -3.51287
HMG20B high mobility group 20B -3.5087
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.49381
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.45199
PDHB pyruvate dehydrogenase (lipoamide) beta -3.45063
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -3.44502
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.40941
DENND2D DENN/MADD domain containing 2D -3.39012
NHLRC2 NHL repeat containing 2 -3.38904
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -3.37771
TP53 tumor protein p53 -3.33995
RHOT1 ras homolog family member T1 -3.32915
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.32342
CCNB2 cyclin B2 -3.31977
FBXO34 F-box protein 34 -3.30896
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.30295
DOCK1 dedicator of cytokinesis 1 -3.29107
ANGEL1 angel homolog 1 (Drosophila) -3.28353
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.26639
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -3.26606
CRYZ crystallin, zeta (quinone reductase) -3.23956
NUP133 nucleoporin 133kDa -3.23756
SLC35F2 solute carrier family 35, member F2 -3.23696
AP5M1 adaptor-related protein complex 5, mu 1 subunit -3.22655
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.2235
NIPSNAP2 nipsnap homolog 2 -3.21497
CHL1 cell adhesion molecule L1-like -3.19459
PROS1 protein S (alpha) -3.18118
SHPK sedoheptulokinase -3.15155
DCK deoxycytidine kinase -3.1483
CDC25B cell division cycle 25B -3.13974
ZNF248 zinc finger protein 248 -3.13553
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.12796
ATP5PO ATP synthase peripheral stalk subunit OSCP -3.12283
LBR lamin B receptor -3.12266
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -3.11449
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -3.09543
ARHGAP19 Rho GTPase activating protein 19 -3.08336
NCAPD2 non-SMC condensin I complex, subunit D2 -3.0782
SPTSSA serine palmitoyltransferase, small subunit A -3.07539
OXCT1 3-oxoacid CoA transferase 1 -3.06037
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.04955
COASY CoA synthase -3.04591
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -3.04456
CD320 CD320 molecule -3.04374
TMEM187 transmembrane protein 187 -3.0357
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -3.02832
CTSG cathepsin G -3.02456
TRIM66 tripartite motif containing 66 -3.02155
DHRS11 dehydrogenase/reductase (SDR family) member 11 -3.01678
STMN1 stathmin 1 -3.01073
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -3.00438
CDK1 cyclin-dependent kinase 1 -3.00313
DLAT dihydrolipoamide S-acetyltransferase -3.00043
MSL1 male-specific lethal 1 homolog (Drosophila) -2.99985
PEX19 peroxisomal biogenesis factor 19 -2.99788
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.97253
TBC1D5 TBC1 domain family, member 5 -2.96703
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.96647
SYPL1 synaptophysin-like 1 -2.96375
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -2.96081
GET1 guided entry of tail-anchored proteins factor 1 -2.9597
KIF4A kinesin family member 4A -2.95823
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.95475
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.93771
BBS10 Bardet-Biedl syndrome 10 -2.93218
ELOVL6 ELOVL fatty acid elongase 6 -2.93012
ATP5F1A ATP synthase F1 subunit alpha -2.92986
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.92866
SNUPN snurportin 1 -2.9261
OXR1 oxidation resistance 1 -2.92405
MRPL39 mitochondrial ribosomal protein L39 -2.92015
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.91317
BMPR1A bone morphogenetic protein receptor, type IA -2.91231
KIF14 kinesin family member 14 -2.90981
NNT nicotinamide nucleotide transhydrogenase -2.89889
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.89653
ANKRD17 ankyrin repeat domain 17 -2.87493
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.87402
FPGS folylpolyglutamate synthase -2.86495
CASC3 cancer susceptibility candidate 3 -2.86296
TSC22D3 TSC22 domain family, member 3 -2.86007
TSKU tsukushi, small leucine rich proteoglycan -2.85575
SYNJ2BP synaptojanin 2 binding protein -2.85426
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.84297
USP19 ubiquitin specific peptidase 19 -2.84108
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -2.8399
SKIC2 SKI2 subunit of superkiller complex -2.83001
SREBF2 sterol regulatory element binding transcription factor 2 -2.82676
SRP9 signal recognition particle 9kDa -2.8247
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.80266
CUTC cutC copper transporter -2.7991
ICE1 interactor of little elongation complex ELL subunit 1 -2.79817
MDH1 malate dehydrogenase 1, NAD (soluble) -2.7935
TCERG1 transcription elongation regulator 1 -2.79203
POGK pogo transposable element with KRAB domain -2.79185
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.79099
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.78828
FLOT2 flotillin 2 -2.78724
CCNG1 cyclin G1 -2.78228
GOLPH3L golgi phosphoprotein 3-like -2.77965
DEAF1 DEAF1 transcription factor -2.77949
AKAP7 A kinase (PRKA) anchor protein 7 -2.77812
PSRC1 proline/serine-rich coiled-coil 1 -2.7776
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.76424
DNAAF2 dynein, axonemal, assembly factor 2 -2.76113
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.74665
WDR5B WD repeat domain 5B -2.73807
AFG3L2 AFG3-like AAA ATPase 2 -2.73786
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.73691
ZNF83 zinc finger protein 83 -2.73424
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.73147
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.73112
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.71955
TTC19 tetratricopeptide repeat domain 19 -2.71417
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.71378
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.71124
JADE2 jade family PHD finger 2 -2.70668
ORAI3 ORAI calcium release-activated calcium modulator 3 -2.70588
KAT2A K(lysine) acetyltransferase 2A -2.69914
MBIP MAP3K12 binding inhibitory protein 1 -2.69363
PFAS phosphoribosylformylglycinamidine synthase -2.68655
MAT2B methionine adenosyltransferase II, beta -2.67803
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -2.67775
MRPS33 mitochondrial ribosomal protein S33 -2.67478
TXNRD3 thioredoxin reductase 3 -2.67289
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.66779
ZFC3H1 zinc finger, C3H1-type containing -2.66652
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.66434
NEK9 NIMA-related kinase 9 -2.66067
PRR15L proline rich 15-like -2.65642
BIRC5 baculoviral IAP repeat containing 5 -2.65551
PARP16 poly (ADP-ribose) polymerase family, member 16 -2.65301
MOAP1 modulator of apoptosis 1 -2.64551
EAPP E2F-associated phosphoprotein -2.64092
ATF6 activating transcription factor 6 -2.63682
MRPS22 mitochondrial ribosomal protein S22 -2.63642
ASPA aspartoacylase -2.6314
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.61631
AMT aminomethyltransferase -2.61162
METRN meteorin, glial cell differentiation regulator -2.60982
SKAP2 src kinase associated phosphoprotein 2 -2.60706
HAT1 histone acetyltransferase 1 -2.60425
PSIP1 PC4 and SFRS1 interacting protein 1 -2.59969
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.59781
FAM20B family with sequence similarity 20, member B -2.59609
ZXDC ZXD family zinc finger C -2.59185
SERF1A small EDRK-rich factor 1A (telomeric) -2.59138
PRKCD protein kinase C, delta -2.58275
INTS3 integrator complex subunit 3 -2.5758
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.57328
TASOR transcription activation suppressor -2.56839
FASTKD1 FAST kinase domains 1 -2.56681
PNISR PNN-interacting serine/arginine-rich protein -2.55765
GGNBP2 gametogenetin binding protein 2 -2.55426
SELENOF selenoprotein F -2.55328
TLK2 tousled-like kinase 2 -2.55267
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.55077
MSRB1 methionine sulfoxide reductase B1 -2.54863
MIS18A MIS18 kinetochore protein A -2.54087
SH2B1 SH2B adaptor protein 1 -2.53844
RIDA reactive intermediate imine deaminase A homolog -2.53459
TUFM Tu translation elongation factor, mitochondrial -2.53145
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.53028
CDK4 cyclin-dependent kinase 4 -2.5215
XPC xeroderma pigmentosum, complementation group C -2.51815
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.51478
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.51201
SPAG7 sperm associated antigen 7 -2.50566
UBE3C ubiquitin protein ligase E3C -2.50141
NECAB3 N-terminal EF-hand calcium binding protein 3 -2.50081
TMX1 thioredoxin-related transmembrane protein 1 -2.50042
CLOCK clock circadian regulator -2.50025
CUL5 cullin 5 -2.49547
RPL36 ribosomal protein L36 -2.49492
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.49389
TMEM168 transmembrane protein 168 -2.48959
IMPACT impact RWD domain protein -2.48788
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -2.48606
FASN fatty acid synthase -2.47733
RBL2 retinoblastoma-like 2 -2.47706
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.47566
NEMF nuclear export mediator factor -2.47442
ATRIP ATR interacting protein -2.47288
LARS1 leucyl-tRNA synthetase 1 -2.47195
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.46428
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.45978
DCAF8 DDB1 and CUL4 associated factor 8 -2.45725
FGGY FGGY carbohydrate kinase domain containing -2.45723
ACACA acetyl-CoA carboxylase alpha -2.45562
PDF peptide deformylase (mitochondrial) -2.4546
ATP5ME ATP synthase membrane subunit e -2.45166
FBXO9 F-box protein 9 -2.45055
THTPA thiamine triphosphatase -2.4505
NLRP4 NLR family, pyrin domain containing 4 -2.45048
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.44832
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.44812
ARL17B ADP-ribosylation factor-like 17B -2.4478
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.44675
METTL8 methyltransferase like 8 -2.44068
ZMYM3 zinc finger, MYM-type 3 -2.43971
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.43659
COX7B cytochrome c oxidase subunit VIIb -2.43382
BTBD1 BTB (POZ) domain containing 1 -2.43035
OSBPL8 oxysterol binding protein-like 8 -2.42804
FKTN fukutin -2.42568
MCM9 minichromosome maintenance complex component 9 -2.42555
SCAP SREBF chaperone -2.42441
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.41748
AGK acylglycerol kinase -2.41186
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.4078
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -2.39928
ALOX15 arachidonate 15-lipoxygenase -2.39915
RXRA retinoid X receptor, alpha -2.39713
WDR41 WD repeat domain 41 -2.39626
TUBGCP4 tubulin, gamma complex associated protein 4 -2.39521
TCTN1 tectonic family member 1 -2.38997
USP1 ubiquitin specific peptidase 1 -2.38939
MRS2 MRS2 magnesium transporter -2.38868
TCTN3 tectonic family member 3 -2.38734
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.38352
MEGF9 multiple EGF-like-domains 9 -2.38152
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.38072
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.38009
SEC23A Sec23 homolog A (S. cerevisiae) -2.37963
CCNA2 cyclin A2 -2.3792
ZMYM1 zinc finger, MYM-type 1 -2.37109
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.36499
CREG1 cellular repressor of E1A-stimulated genes 1 -2.36046
MPHOSPH9 M-phase phosphoprotein 9 -2.35506
RABL3 RAB, member of RAS oncogene family-like 3 -2.34853
MPZL1 myelin protein zero-like 1 -2.34755
ZDHHC6 zinc finger, DHHC-type containing 6 -2.34693
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.34444
SIRT3 sirtuin 3 -2.34322
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.33847
PLK1 polo-like kinase 1 -2.33489
PRDX3 peroxiredoxin 3 -2.32963
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.32942
CAAP1 caspase activity and apoptosis inhibitor 1 -2.32642
BTBD2 BTB (POZ) domain containing 2 -2.32558
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.32339
FASTK Fas-activated serine/threonine kinase -2.31832
APOOL apolipoprotein O-like -2.31743
TRAPPC13 trafficking protein particle complex 13 -2.31335
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.31189
TMEM43 transmembrane protein 43 -2.31091
PALB2 partner and localizer of BRCA2 -2.30984
DENND4C DENN/MADD domain containing 4C -2.30964
GRAMD1C GRAM domain containing 1C -2.30658
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.30589
LAPTM4B lysosomal protein transmembrane 4 beta -2.30564
WDR6 WD repeat domain 6 -2.30453
AUH AU RNA binding protein/enoyl-CoA hydratase -2.30358
ZNF587 zinc finger protein 587 -2.3032
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -2.30268
CENPS-CORT CENPS-CORT readthrough -2.302
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.29954
DHCR7 7-dehydrocholesterol reductase -2.29829
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.29814
SUB1 SUB1 homolog (S. cerevisiae) -2.29791
COX11 COX11 cytochrome c oxidase copper chaperone -2.2975
HLTF helicase-like transcription factor -2.2974
MRPS30 mitochondrial ribosomal protein S30 -2.29584
GSTK1 glutathione S-transferase kappa 1 -2.29556
HMG20A high mobility group 20A -2.2903
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -2.28679
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.28468
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.28382
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.2784
FASTKD3 FAST kinase domains 3 -2.27795
EPHA1 EPH receptor A1 -2.27661
TCTA T-cell leukemia translocation altered -2.27372
TRIM52 tripartite motif containing 52 -2.27173
THAP11 THAP domain containing 11 -2.27162
SLC38A6 solute carrier family 38, member 6 -2.27097
AKAP11 A kinase (PRKA) anchor protein 11 -2.27065
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.26755
BTN3A1 butyrophilin, subfamily 3, member A1 -2.26411
ATP5F1D ATP synthase F1 subunit delta -2.2631
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.26242
ZFYVE16 zinc finger, FYVE domain containing 16 -2.26207
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.26129
TMEM254 transmembrane protein 254 -2.26076
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.25747
AASS aminoadipate-semialdehyde synthase -2.25622
RWDD2B RWD domain containing 2B -2.25612
URI1 URI1, prefoldin-like chaperone -2.2523
CHEK2 checkpoint kinase 2 -2.25178
CYCS cytochrome c, somatic -2.25134
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.25104
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.24616
ENOSF1 enolase superfamily member 1 -2.24601
CCDC51 coiled-coil domain containing 51 -2.24575
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.24481
RAN RAN, member RAS oncogene family -2.24455
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.24107
NAT10 N-acetyltransferase 10 (GCN5-related) -2.24007
PRUNE1 prune exopolyphosphatase 1 -2.23947
MDN1 MDN1, midasin homolog (yeast) -2.23946
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -2.2394
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.23791
REPIN1 replication initiator 1 -2.23711
CYFIP2 cytoplasmic FMR1 interacting protein 2 -2.23703
PHF2 PHD finger protein 2 -2.23585
MFN1 mitofusin 1 -2.23538
SUOX sulfite oxidase -2.23304
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.22769
SPPL2A signal peptide peptidase like 2A -2.22122
YME1L1 YME1-like 1 ATPase -2.21999
RPL39L ribosomal protein L39-like -2.21946
ZNF318 zinc finger protein 318 -2.21863
MTREX Mtr4 exosome RNA helicase -2.21654
NUP205 nucleoporin 205kDa -2.21643
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.21474
GAA glucosidase, alpha; acid -2.21329
SIRT5 sirtuin 5 -2.21306
PCYOX1L prenylcysteine oxidase 1 like -2.21212
HOXB9 homeobox B9 -2.21114
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.2109
BLCAP bladder cancer associated protein -2.20901
DSG2 desmoglein 2 -2.2055
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.2032
KIF11 kinesin family member 11 -2.20179
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.20066
GYS1 glycogen synthase 1 (muscle) -2.2001
SKIC8 SKI8 subunit of superkiller complex -2.19724
BACE2 beta-site APP-cleaving enzyme 2 -2.19673
FAM114A2 family with sequence similarity 114, member A2 -2.19673
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.19444
ZBTB38 zinc finger and BTB domain containing 38 -2.19188
ISCA1 iron-sulfur cluster assembly 1 -2.19146
NUBPL nucleotide binding protein-like -2.18592
ABHD10 abhydrolase domain containing 10 -2.1847
KRTAP5-2 keratin associated protein 5-2 -2.18464
WDR7 WD repeat domain 7 -2.18365
ASB13 ankyrin repeat and SOCS box containing 13 -2.18157
ACY1 aminoacylase 1 -2.1782
PEX12 peroxisomal biogenesis factor 12 -2.1775
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.17517
SLIRP SRA stem-loop interacting RNA binding protein -2.17099
FTO fat mass and obesity associated -2.16693
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -2.16672
DNM1 dynamin 1 -2.16572
KYAT1 kynurenine aminotransferase 1 -2.16523
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -2.1576
TBC1D2B TBC1 domain family, member 2B -2.15616
WASHC4 WASH complex subunit 4 -2.15504
MRPL34 mitochondrial ribosomal protein L34 -2.155
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.15307
MUC4 mucin 4, cell surface associated -2.15223
CETN3 centrin, EF-hand protein, 3 -2.15153
SACS sacsin molecular chaperone -2.1513
XPO1 exportin 1 -2.14927
PRRC2B proline-rich coiled-coil 2B -2.14921
PCNP PEST proteolytic signal containing nuclear protein -2.14785
FBXL5 F-box and leucine-rich repeat protein 5 -2.14645
ACP6 acid phosphatase 6, lysophosphatidic -2.14626
FHL5 four and a half LIM domains 5 -2.1416
SC5D sterol-C5-desaturase -2.13962
FAM234B family with sequence similarity 234 member B -2.13842
POGZ pogo transposable element with ZNF domain -2.13413
TXNDC9 thioredoxin domain containing 9 -2.13373
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.13337
PARG poly (ADP-ribose) glycohydrolase -2.12761
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.12736
FHIT fragile histidine triad -2.12645
PNPO pyridoxamine 5'-phosphate oxidase -2.12596
SEPTIN10 septin 10 -2.12403
MKRN2 makorin ring finger protein 2 -2.12363
NPM3 nucleophosmin/nucleoplasmin 3 -2.11972
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.11893
SEC31B SEC31 homolog B (S. cerevisiae) -2.11722
DPY19L4 dpy-19-like 4 (C. elegans) -2.11561
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.11473
DVL3 dishevelled segment polarity protein 3 -2.11406
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -2.11196
ATP5PF ATP synthase peripheral stalk subunit F6 -2.11099
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.10525
UFL1 UFM1-specific ligase 1 -2.10445
CTSO cathepsin O -2.09706
ATP5F1C ATP synthase F1 subunit gamma -2.0927
SORBS3 sorbin and SH3 domain containing 3 -2.09258
ICE2 interactor of little elongation complex ELL subunit 2 -2.09134
F8 coagulation factor VIII, procoagulant component -2.09134
KAT7 K(lysine) acetyltransferase 7 -2.09046
HELZ helicase with zinc finger -2.08577
HAVCR1 hepatitis A virus cellular receptor 1 -2.08573
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.08534
GOLGA8A golgin A8 family, member A -2.08492
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -2.08442
TIPRL TOR signaling pathway regulator -2.08155
NFIL3 nuclear factor, interleukin 3 regulated -2.07579
MRPL12 mitochondrial ribosomal protein L12 -2.07366
OSMR oncostatin M receptor -2.07321
TKT transketolase -2.07312
LRRC20 leucine rich repeat containing 20 -2.07117
SLC41A3 solute carrier family 41, member 3 -2.07041
RNFT2 ring finger protein, transmembrane 2 -2.06926
ZNHIT3 zinc finger, HIT-type containing 3 -2.06853
EPS15 epidermal growth factor receptor pathway substrate 15 -2.06783
PRPF4 pre-mRNA processing factor 4 -2.06764
ERLIN1 ER lipid raft associated 1 -2.06722
CCDC25 coiled-coil domain containing 25 -2.06706
DMAC2L distal membrane arm assembly component 2 like -2.06549
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.06423
PANK3 pantothenate kinase 3 -2.06412
PTCH2 patched 2 -2.05406
ZNF106 zinc finger protein 106 -2.05126
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.05087
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -2.04913
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.0473
PLSCR4 phospholipid scramblase 4 -2.04723
FKBP3 FK506 binding protein 3, 25kDa -2.04501
GEMIN2 gem (nuclear organelle) associated protein 2 -2.04468
RYK receptor-like tyrosine kinase -2.04114
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.04113
MORC3 MORC family CW-type zinc finger 3 -2.04082
ASDURF ASNSD1 upstream open reading frame -2.04078
ZNF514 zinc finger protein 514 -2.03617
GDE1 glycerophosphodiester phosphodiesterase 1 -2.03606
EXD2 exonuclease 3'-5' domain containing 2 -2.03255
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.03126
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.03041
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.0304
WDR37 WD repeat domain 37 -2.02953
PFKM phosphofructokinase, muscle -2.02859
CYREN cell cycle regulator of NHEJ -2.02843
TASOR2 transcription activation suppressor family member 2 -2.02773
CPVL carboxypeptidase, vitellogenic-like -2.02748
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.02735
LYRM9 LYR motif containing 9 -2.0273
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.02666
FOXC1 forkhead box C1 -2.02543
SSH3 slingshot protein phosphatase 3 -2.02303
UFM1 ubiquitin-fold modifier 1 -2.02296
DNAAF5 dynein, axonemal, assembly factor 5 -2.02275
ZNF518A zinc finger protein 518A -2.02213
PUM2 pumilio RNA-binding family member 2 -2.02104
F2R coagulation factor II (thrombin) receptor -2.01936
THAP12 THAP domain containing 12 -2.01814
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.01715
CIC capicua transcriptional repressor -2.01451
GOLM1 golgi membrane protein 1 -2.0111
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.01072
MOCS2 molybdenum cofactor synthesis 2 -2.01014
EML4 echinoderm microtubule associated protein like 4 -2.00944
HMGB3 high mobility group box 3 -2.00926
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -2.00744
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.00675
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -2.00669
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.00668
RMI1 RecQ mediated genome instability 1 -2.00617
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.00516
FOXM1 forkhead box M1 -2.00273
MRTFB myocardin related transcription factor B -2.00221
PAIP1 poly(A) binding protein interacting protein 1 -2.0014