CRCGN016_MCF10A.WT.HP_24H:L11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description disulfiram 33.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

994 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GADD45B growth arrest and DNA-damage-inducible, beta 9.89423
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 9.58213
HSPA1A heat shock 70kDa protein 1A 9.3969
FOS FBJ murine osteosarcoma viral oncogene homolog 8.52748
TRIB1 tribbles pseudokinase 1 8.32726
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 8.24256
RGS2 regulator of G-protein signaling 2 7.91021
CEMIP2 cell migration inducing hyaluronidase 2 7.75554
ALAS1 5'-aminolevulinate synthase 1 7.44738
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 7.36124
HSPA1B heat shock 70kDa protein 1B 7.1686
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 7.1598
HMOX1 heme oxygenase 1 6.78745
NUCB2 nucleobindin 2 6.4946
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 6.44415
CHIC2 cysteine-rich hydrophobic domain 2 6.16786
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 6.04094
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.66228
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.58549
ADRB2 adrenoceptor beta 2, surface 5.49412
BAG3 BCL2-associated athanogene 3 5.49339
HSPA6 heat shock 70kDa protein 6 (HSP70B') 5.45602
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 5.42822
MMP1 matrix metallopeptidase 1 5.41807
FHL2 four and a half LIM domains 2 5.32501
COMP cartilage oligomeric matrix protein 5.28109
SQSTM1 sequestosome 1 5.27171
CXCL2 chemokine (C-X-C motif) ligand 2 5.13399
CADM1 cell adhesion molecule 1 5.1008
PPP1R15A protein phosphatase 1, regulatory subunit 15A 4.98536
IGFBP3 insulin-like growth factor binding protein 3 4.92788
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.86944
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.66566
RNASE7 ribonuclease, RNase A family, 7 4.6652
SLC35B1 solute carrier family 35, member B1 4.52925
TNIP1 TNFAIP3 interacting protein 1 4.52901
WIF1 WNT inhibitory factor 1 4.4857
CCL3L3 chemokine (C-C motif) ligand 3-like 3 4.48329
IER5 immediate early response 5 4.40881
RTF2 replication termination factor 2 4.37515
TUFT1 tuftelin 1 4.35033
ARID5B AT rich interactive domain 5B (MRF1-like) 4.31233
GCC1 GRIP and coiled-coil domain containing 1 4.1809
RBM42 RNA binding motif protein 42 4.18089
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 4.09776
GOLT1B golgi transport 1B 4.09275
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 4.06217
CXCR4 chemokine (C-X-C motif) receptor 4 4.01748
NRBF2 nuclear receptor binding factor 2 4.00987
RBM22 RNA binding motif protein 22 3.96676
DUSP14 dual specificity phosphatase 14 3.90757
UGDH UDP-glucose 6-dehydrogenase 3.90534
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.88979
NOSIP nitric oxide synthase interacting protein 3.88899
MON1B MON1 secretory trafficking family member B 3.81015
IER2 immediate early response 2 3.81007
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.80261
LIN37 lin-37 DREAM MuvB core complex component 3.78407
ATG101 autophagy related 101 3.78014
EGR1 early growth response 1 3.75632
IL1B interleukin 1, beta 3.73685
TXNRD1 thioredoxin reductase 1 3.719
ATF3 activating transcription factor 3 3.71039
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.692
LRP10 low density lipoprotein receptor-related protein 10 3.65402
IFRD1 interferon-related developmental regulator 1 3.6304
PLA2G15 phospholipase A2, group XV 3.60412
CDPF1 cysteine-rich, DPF motif domain containing 1 3.60274
STX4 syntaxin 4 3.58428
TBPL1 TBP-like 1 3.54699
INHBA inhibin, beta A 3.52804
JMJD6 jumonji domain containing 6 3.46492
FOSB FBJ murine osteosarcoma viral oncogene homolog B 3.45973
BAMBI BMP and activin membrane-bound inhibitor 3.43213
FBXL12 F-box and leucine-rich repeat protein 12 3.42686
IRF7 interferon regulatory factor 7 3.40848
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 3.40566
ZNF212 zinc finger protein 212 3.39615
FRS2 fibroblast growth factor receptor substrate 2 3.39446
ZNF365 zinc finger protein 365 3.39065
RASAL2 RAS protein activator like 2 3.3779
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 3.35691
CTSL cathepsin L 3.35391
RSF1 remodeling and spacing factor 1 3.34611
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 3.33097
MSX2 msh homeobox 2 3.30832
MMP10 matrix metallopeptidase 10 3.26931
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.26931
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.2673
HBEGF heparin-binding EGF-like growth factor 3.25883
BTG1 B-cell translocation gene 1, anti-proliferative 3.2556
LOC128125814 uncharacterized LOC128125814 3.25347
RAB31 RAB31, member RAS oncogene family 3.23342
RND1 Rho family GTPase 1 3.19999
GADD45G growth arrest and DNA-damage-inducible, gamma 3.19551
GABARAPL1 GABA(A) receptor-associated protein like 1 3.1777
ZBTB10 zinc finger and BTB domain containing 10 3.17264
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.17232
RMC1 regulator of MON1-CCZ1 3.1645
TUBB6 tubulin, beta 6 class V 3.14024
IST1 increased sodium tolerance 1 homolog (yeast) 3.13975
ADRM1 adhesion regulating molecule 1 3.13694
FRMD4B FERM domain containing 4B 3.1368
SDC4 syndecan 4 3.09505
SP140L SP140 nuclear body protein-like 3.09431
CSRNP2 cysteine-serine-rich nuclear protein 2 3.08481
UBQLN2 ubiquilin 2 3.08455
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 3.07286
AFF4 AF4/FMR2 family, member 4 3.0597
STX3 syntaxin 3 3.05756
CARS1 cysteinyl-tRNA synthetase 1 3.05337
R3HCC1L R3H domain and coiled-coil containing 1-like 3.05164
FICD FIC domain containing 3.03823
ELMO2 engulfment and cell motility 2 3.03316
CTNNBL1 catenin, beta like 1 3.03289
ZNF222 zinc finger protein 222 3.01777
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 3.01599
FOXF2 forkhead box F2 3.0093
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.00754
TP53BP2 tumor protein p53 binding protein 2 2.97716
ZNF668 zinc finger protein 668 2.96078
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.95945
SMIM40 small integral membrane protein 40 2.95828
CANT1 calcium activated nucleotidase 1 2.94991
MICB MHC class I polypeptide-related sequence B 2.94661
OXSR1 oxidative stress responsive 1 2.94506
PXDC1 PX domain containing 1 2.91161
TMEM40 transmembrane protein 40 2.88629
DYNLT3 dynein, light chain, Tctex-type 3 2.87673
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.87627
STX5 syntaxin 5 2.87272
PTHLH parathyroid hormone-like hormone 2.86572
EDN1 endothelin 1 2.85995
GARS1 glycyl-tRNA synthetase 1 2.85938
SMAD3 SMAD family member 3 2.85807
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.85442
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.85399
NACAD NAC alpha domain containing 2.8482
ISG20 interferon stimulated exonuclease gene 20kDa 2.84658
HYOU1 hypoxia up-regulated 1 2.83807
MYL9 myosin, light chain 9, regulatory 2.83694
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.83036
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.81821
KMT5A lysine methyltransferase 5A 2.8162
STAU1 staufen double-stranded RNA binding protein 1 2.79352
PEA15 phosphoprotein enriched in astrocytes 15 2.79275
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.79274
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.77627
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.76909
FASTKD5 FAST kinase domains 5 2.7605
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.75993
DDA1 DET1 and DDB1 associated 1 2.75935
RAP1GAP RAP1 GTPase activating protein 2.75674
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.75117
SEPHS2 selenophosphate synthetase 2 2.75005
KRT34 keratin 34, type I 2.74718
RAP1B RAP1B, member of RAS oncogene family 2.74344
H2AC19 H2A clustered histone 19 2.73768
KLF4 Kruppel-like factor 4 (gut) 2.73636
ABHD4 abhydrolase domain containing 4 2.73472
NDEL1 nudE neurodevelopment protein 1-like 1 2.73005
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.72239
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.72012
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.71688
LIF leukemia inhibitory factor 2.71291
AGR2 anterior gradient 2 2.70917
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.70469
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.70227
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.70218
LARP6 La ribonucleoprotein domain family, member 6 2.70079
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.68982
GPATCH1 G patch domain containing 1 2.68229
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.67587
MACO1 macoilin 1 2.67221
ZNF155 zinc finger protein 155 2.67183
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.66899
ADM adrenomedullin 2.6569
FYN FYN proto-oncogene, Src family tyrosine kinase 2.64899
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.64693
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.6443
ARL14 ADP-ribosylation factor-like 14 2.64336
PPY pancreatic polypeptide 2.64171
SLC38A12 solute carrier family 38 member 12 2.63403
C6ORF89 chromosome 6 open reading frame 89 2.62914
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.62001
DEPP1 DEPP autophagy regulator 1 2.61385
MSMB microseminoprotein, beta- 2.61135
BUD31 BUD31 homolog (S. cerevisiae) 2.60801
ATF4 activating transcription factor 4 2.60538
TMEM39A transmembrane protein 39A 2.59894
CYB5R2 cytochrome b5 reductase 2 2.59302
NIBAN1 niban apoptosis regulator 1 2.59218
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.59159
CIRSR corepressor of RBPJ and splicing regulator 2.59113
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.58432
COL9A2 collagen, type IX, alpha 2 2.58102
TMEM127 transmembrane protein 127 2.58052
ATOSB atos homolog B 2.56928
DDRGK1 DDRGK domain containing 1 2.56835
YOD1 YOD1 deubiquitinase 2.56437
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.56309
TPST2 tyrosylprotein sulfotransferase 2 2.55817
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.54142
STIP1 stress-induced phosphoprotein 1 2.54092
ARC activity-regulated cytoskeleton-associated protein 2.53822
ZC3H7A zinc finger CCCH-type containing 7A 2.53464
PSEN2 presenilin 2 2.53265
BRMS1L breast cancer metastasis-suppressor 1-like 2.52839
IL11 interleukin 11 2.52593
IL2RA interleukin 2 receptor, alpha 2.524
STX11 syntaxin 11 2.52331
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.52212
HSPH1 heat shock 105kDa/110kDa protein 1 2.51826
YIPF3 Yip1 domain family, member 3 2.51535
TBC1D22B TBC1 domain family, member 22B 2.51325
PKN1 protein kinase N1 2.51312
THSD1 thrombospondin, type I, domain containing 1 2.51137
SULF1 sulfatase 1 2.5071
AMOTL2 angiomotin like 2 2.5052
ELF4 E74-like factor 4 (ets domain transcription factor) 2.49768
CATSPERB catsper channel auxiliary subunit beta 2.49601
LAMB3 laminin, beta 3 2.49573
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.49282
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.49267
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.49165
CGB8 chorionic gonadotropin, beta polypeptide 8 2.49117
SPAG9 sperm associated antigen 9 2.48963
UFD1 ubiquitin recognition factor in ER associated degradation 1 2.48927
RHOG ras homolog family member G 2.48873
BMP6 bone morphogenetic protein 6 2.48805
OPTN optineurin 2.48241
MMP3 matrix metallopeptidase 3 2.48162
SMIM29 small integral membrane protein 29 2.47553
TICAM1 toll-like receptor adaptor molecule 1 2.47363
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.47325
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.46274
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.46273
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.46256
TIMP2 TIMP metallopeptidase inhibitor 2 2.46163
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.46085
NUP58 nucleoporin 58 2.46026
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.45487
EIF5A2 eukaryotic translation initiation factor 5A2 2.45335
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.45216
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.45203
COL17A1 collagen, type XVII, alpha 1 2.44439
HTATSF1 HIV-1 Tat specific factor 1 2.44162
HDAC9 histone deacetylase 9 2.43129
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.42657
TEX14 testis expressed 14 2.42604
JOSD1 Josephin domain containing 1 2.42491
UPP1 uridine phosphorylase 1 2.42131
RNF25 ring finger protein 25 2.4176
IL23A interleukin 23, alpha subunit p19 2.41724
BCAS1 breast carcinoma amplified sequence 1 2.41564
BYSL bystin-like 2.412
AAMDC adipogenesis associated, Mth938 domain containing 2.40882
RAB8B RAB8B, member RAS oncogene family 2.39924
UBXN1 UBX domain protein 1 2.39531
THBS1 thrombospondin 1 2.39011
SPHK1 sphingosine kinase 1 2.38582
ARID5A AT rich interactive domain 5A (MRF1-like) 2.38482
PDZK1IP1 PDZK1 interacting protein 1 2.38468
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.38182
UBTD1 ubiquitin domain containing 1 2.38145
ALOXE3 arachidonate lipoxygenase 3 2.3795
WFS1 Wolfram syndrome 1 (wolframin) 2.37715
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.37498
CCL20 chemokine (C-C motif) ligand 20 2.37448
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.37402
HYI hydroxypyruvate isomerase (putative) 2.3733
HOMER3 homer scaffolding protein 3 2.36776
GPR137B G protein-coupled receptor 137B 2.3666
DYNLRB1 dynein, light chain, roadblock-type 1 2.36435
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.36213
DUSP4 dual specificity phosphatase 4 2.35389
C18ORF25 chromosome 18 open reading frame 25 2.35094
EHD1 EH-domain containing 1 2.34724
SAP30BP SAP30 binding protein 2.34712
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.34597
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.3437
SBDS Shwachman-Bodian-Diamond syndrome 2.34075
STBD1 starch binding domain 1 2.34059
GOSR2 golgi SNAP receptor complex member 2 2.33834
CD2AP CD2-associated protein 2.33701
JUN jun proto-oncogene 2.33546
ZNF79 zinc finger protein 79 2.33462
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.33304
PDPN podoplanin 2.333
STYK1 serine/threonine/tyrosine kinase 1 2.33278
TCP11L1 t-complex 11, testis-specific-like 1 2.33228
CAVIN3 caveolae associated protein 3 2.3284
BIRC3 baculoviral IAP repeat containing 3 2.32828
GPKOW G patch domain and KOW motifs 2.32582
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 2.32382
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.32372
CTAG2 cancer/testis antigen 2 2.32336
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.32136
NTAN1 N-terminal asparagine amidase 2.3199
GDI1 GDP dissociation inhibitor 1 2.31862
FIP1L1 factor interacting with PAPOLA and CPSF1 2.31531
NPC1 Niemann-Pick disease, type C1 2.31489
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.31473
EFNA1 ephrin-A1 2.31308
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.31265
ZNF586 zinc finger protein 586 2.31122
OSBPL2 oxysterol binding protein-like 2 2.30863
LIG4 ligase IV, DNA, ATP-dependent 2.30853
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.30601
CSRP2 cysteine and glycine-rich protein 2 2.30468
SH2D2A SH2 domain containing 2A 2.30237
ZBTB17 zinc finger and BTB domain containing 17 2.30109
NUAK1 NUAK family, SNF1-like kinase, 1 2.30084
TFIP11 tuftelin interacting protein 11 2.3007
ZNF263 zinc finger protein 263 2.29761
GSDMB gasdermin B 2.29649
AARS1 alanyl-tRNA synthetase 1 2.29528
CCL4 chemokine (C-C motif) ligand 4 2.29468
GATA2 GATA binding protein 2 2.29358
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.29186
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 2.29176
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.28511
VSTM4 V-set and transmembrane domain containing 4 2.2849
PLAAT2 phospholipase A and acyltransferase 2 2.28138
RTN4 reticulon 4 2.28133
AMIGO2 adhesion molecule with Ig-like domain 2 2.28019
HSPA8 heat shock 70kDa protein 8 2.27874
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.27817
GREM1 gremlin 1, DAN family BMP antagonist 2.27738
ELOVL4 ELOVL fatty acid elongase 4 2.27694
ULBP2 UL16 binding protein 2 2.27229
PSG5 pregnancy specific beta-1-glycoprotein 5 2.2665
CAVIN1 caveolae associated protein 1 2.26481
TERF2IP telomeric repeat binding factor 2, interacting protein 2.26142
RINT1 RAD50 interactor 1 2.26021
TOX4 TOX high mobility group box family member 4 2.26001
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.25784
PALM paralemmin 2.25631
SAR1A secretion associated, Ras related GTPase 1A 2.2553
PLAUR plasminogen activator, urokinase receptor 2.25114
TESK1 testis-specific kinase 1 2.24841
SAMD9 sterile alpha motif domain containing 9 2.24799
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.24323
DAZ2 deleted in azoospermia 2 2.2426
CD101 CD101 molecule 2.23989
STK10 serine/threonine kinase 10 2.23906
CD83 CD83 molecule 2.23679
PAGE1 P antigen family, member 1 (prostate associated) 2.23443
RNF103 ring finger protein 103 2.23102
MRPL18 mitochondrial ribosomal protein L18 2.23048
PARP8 poly (ADP-ribose) polymerase family, member 8 2.23008
YIPF1 Yip1 domain family, member 1 2.22961
CA2 carbonic anhydrase II 2.22915
DOK2 docking protein 2, 56kDa 2.22805
ARMCX3 armadillo repeat containing, X-linked 3 2.22701
RHOB ras homolog family member B 2.22334
KIF17 kinesin family member 17 2.22194
HSPA2 heat shock 70kDa protein 2 2.22003
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.2156
SPATA2L spermatogenesis associated 2-like 2.21404
IFNG interferon, gamma 2.21378
CCR2 chemokine (C-C motif) receptor 2 2.21363
TWF2 twinfilin actin binding protein 2 2.21343
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.20982
GBX2 gastrulation brain homeobox 2 2.20855
GPATCH2 G patch domain containing 2 2.19908
RASL11B RAS-like, family 11, member B 2.19605
AJAP1 adherens junctions associated protein 1 2.19336
H2BC12 H2B clustered histone 12 2.18974
PMP22 peripheral myelin protein 22 2.1896
ETV6 ets variant 6 2.1809
MTCH1 mitochondrial carrier 1 2.17996
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.17875
FLT3LG fms-related tyrosine kinase 3 ligand 2.17793
ZNF426 zinc finger protein 426 2.17731
SEC62 SEC62 homolog (S. cerevisiae) 2.1762
ZNF473 zinc finger protein 473 2.17459
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.17391
SLC38A2 solute carrier family 38, member 2 2.16974
GLRX glutaredoxin (thioltransferase) 2.16747
TPM1 tropomyosin 1 (alpha) 2.16681
NUPR1 nuclear protein, transcriptional regulator, 1 2.15964
LGALS1 lectin, galactoside-binding, soluble, 1 2.15828
IGF1R insulin-like growth factor 1 receptor 2.15264
GC group-specific component (vitamin D binding protein) 2.15027
STK17A serine/threonine kinase 17a 2.14803
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.14777
NANS N-acetylneuraminic acid synthase 2.14724
JUND jun D proto-oncogene 2.14456
ZNF227 zinc finger protein 227 2.14348
CALCOCO1 calcium binding and coiled-coil domain 1 2.143
RUSC2 RUN and SH3 domain containing 2 2.14029
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.13921
CDC34 cell division cycle 34 2.13573
CALCOCO2 calcium binding and coiled-coil domain 2 2.13311
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.12341
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.12255
ZBED2 zinc finger, BED-type containing 2 2.12022
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.11911
COL4A1 collagen, type IV, alpha 1 2.11568
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.11211
IL5 interleukin 5 2.11135
SNF8 SNF8, ESCRT-II complex subunit 2.11068
GAL3ST1 galactose-3-O-sulfotransferase 1 2.1097
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2.10877
IFI35 interferon-induced protein 35 2.10467
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2.10401
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.10306
SKIL SKI-like proto-oncogene 2.10226
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.10108
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.10093
OCLN occludin 2.09732
SNW1 SNW domain containing 1 2.09666
DEGS1 delta(4)-desaturase, sphingolipid 1 2.09374
COL8A2 collagen, type VIII, alpha 2 2.09352
GMEB2 glucocorticoid modulatory element binding protein 2 2.09349
ESM1 endothelial cell-specific molecule 1 2.09297
EDC3 enhancer of mRNA decapping 3 2.08984
SLC61A1 solute carrier family 61 member 1 2.08523
SP100 SP100 nuclear antigen 2.08483
H2BC4 H2B clustered histone 4 2.08297
SOCS1 suppressor of cytokine signaling 1 2.07926
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.07512
ZNF10 zinc finger protein 10 2.07434
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.07365
EIF1 eukaryotic translation initiation factor 1 2.07271
H2BC9 H2B clustered histone 9 2.0725
C1R complement component 1, r subcomponent 2.07205
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.0702
JCAD junctional cadherin 5 associated 2.06987
MUC13 mucin 13, cell surface associated 2.0698
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.0623
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.05992
IL6 interleukin 6 2.05991
ATP11B ATPase, class VI, type 11B 2.0595
BRD2 bromodomain containing 2 2.05715
SFMBT1 Scm-like with four mbt domains 1 2.05668
CCDC88C coiled-coil domain containing 88C 2.05644
MVP major vault protein 2.05313
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2.05238
MYH9 myosin, heavy chain 9, non-muscle 2.05162
TBCB tubulin folding cofactor B 2.04965
GRAPL GRB2-related adaptor protein-like 2.0487
CA6 carbonic anhydrase VI 2.04846
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.04793
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.04392
FOXD1 forkhead box D1 2.0437
ITCH itchy E3 ubiquitin protein ligase 2.04106
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.03816
DSPP dentin sialophosphoprotein 2.03771
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.03438
IL18RAP interleukin 18 receptor accessory protein 2.03436
FOXL2 forkhead box L2 2.03405
KIF3B kinesin family member 3B 2.03359
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.03322
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.03255
AKAP17A A kinase (PRKA) anchor protein 17A 2.03126
CAB39 calcium binding protein 39 2.03088
SMAD7 SMAD family member 7 2.03014
GADD45A growth arrest and DNA-damage-inducible, alpha 2.02835
TOR1A torsin family 1, member A (torsin A) 2.027
ZHX2 zinc fingers and homeoboxes 2 2.02563
CBARP CACN subunit beta associated regulatory protein 2.02547
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.02526
FGF18 fibroblast growth factor 18 2.02498
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.02127
TM4SF4 transmembrane 4 L six family member 4 2.021
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 2.01769
LGALS4 lectin, galactoside-binding, soluble, 4 2.01637
PPARD peroxisome proliferator-activated receptor delta 2.01607
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.01302
DOCK5 dedicator of cytokinesis 5 2.00948
PWWP3A PWWP domain containing 3A, DNA repair factor 2.00943
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 2.00913
CDKN2AIP CDKN2A interacting protein 2.00814
DAPK3 death-associated protein kinase 3 2.00684
CEMIP cell migration inducing protein, hyaluronan binding 2.0063
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.00575
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.00477
SNIP1 Smad nuclear interacting protein 1 2.00442
TMEM132A transmembrane protein 132A 2.00359
LAMC2 laminin, gamma 2 2.00224
LSR lipolysis stimulated lipoprotein receptor 2.00195
ANKLE2 ankyrin repeat and LEM domain containing 2 2.00159

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -7.9303
HADH hydroxyacyl-CoA dehydrogenase -7.40802
OXCT1 3-oxoacid CoA transferase 1 -7.27986
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.86169
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -6.26352
MSMO1 methylsterol monooxygenase 1 -6.22891
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.67256
PCCB propionyl CoA carboxylase, beta polypeptide -5.65239
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.62415
DDIT4 DNA-damage-inducible transcript 4 -5.47219
CDK4 cyclin-dependent kinase 4 -5.3531
COG2 component of oligomeric golgi complex 2 -5.09136
ADI1 acireductone dioxygenase 1 -5.08792
C1QBP complement component 1, q subcomponent binding protein -5.02542
PGM1 phosphoglucomutase 1 -4.89985
PSRC1 proline/serine-rich coiled-coil 1 -4.89246
TSPAN6 tetraspanin 6 -4.82973
TRAP1 TNF receptor-associated protein 1 -4.79077
PRCP prolylcarboxypeptidase (angiotensinase C) -4.78787
TLCD3A TLC domain containing 3A -4.75429
CPNE3 copine III -4.72149
BACE2 beta-site APP-cleaving enzyme 2 -4.69387
NIPSNAP1 nipsnap homolog 1 (C. elegans) -4.55227
PHKB phosphorylase kinase, beta -4.55087
LBR lamin B receptor -4.52873
CCNB2 cyclin B2 -4.5278
HOXA5 homeobox A5 -4.49881
CRYZ crystallin, zeta (quinone reductase) -4.42507
TOP2A topoisomerase (DNA) II alpha 170kDa -4.40921
NIPSNAP2 nipsnap homolog 2 -4.36627
NCAPD2 non-SMC condensin I complex, subunit D2 -4.31164
CISD1 CDGSH iron sulfur domain 1 -4.28828
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.26649
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.23065
RPA3 replication protein A3, 14kDa -4.14025
GTF2A2 general transcription factor IIA, 2, 12kDa -4.07862
AKAP11 A kinase (PRKA) anchor protein 11 -4.07808
DLAT dihydrolipoamide S-acetyltransferase -4.05139
PPA2 pyrophosphatase (inorganic) 2 -4.0479
DCK deoxycytidine kinase -4.02116
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.01475
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -3.99752
TSPAN3 tetraspanin 3 -3.9491
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -3.94302
CDC20 cell division cycle 20 -3.94225
AP5M1 adaptor-related protein complex 5, mu 1 subunit -3.92049
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.90582
SREBF1 sterol regulatory element binding transcription factor 1 -3.84834
INSIG1 insulin induced gene 1 -3.82819
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.82097
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.81702
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -3.79416
LDHD lactate dehydrogenase D -3.78842
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -3.78249
HEATR1 HEAT repeat containing 1 -3.7699
TMEM187 transmembrane protein 187 -3.75752
ZNF83 zinc finger protein 83 -3.75198
STMN1 stathmin 1 -3.746
SESN1 sestrin 1 -3.73818
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.7261
CD58 CD58 molecule -3.72357
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.69773
CCNA2 cyclin A2 -3.69223
GET1 guided entry of tail-anchored proteins factor 1 -3.68586
MYO5C myosin VC -3.62119
NUP133 nucleoporin 133kDa -3.55006
ATMIN ATM interactor -3.54411
OXA1L oxidase (cytochrome c) assembly 1-like -3.54411
GPHN gephyrin -3.4671
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.44732
CYCS cytochrome c, somatic -3.44225
TCTN1 tectonic family member 1 -3.4382
FKBP3 FK506 binding protein 3, 25kDa -3.39652
TP53 tumor protein p53 -3.3953
ZDHHC6 zinc finger, DHHC-type containing 6 -3.38098
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.38086
FAM216A family with sequence similarity 216, member A -3.3714
TMX1 thioredoxin-related transmembrane protein 1 -3.36586
PRMT3 protein arginine methyltransferase 3 -3.36222
METTL8 methyltransferase like 8 -3.3622
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.34644
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.32798
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.30876
BIRC5 baculoviral IAP repeat containing 5 -3.30824
RHOT1 ras homolog family member T1 -3.29722
ZMYM1 zinc finger, MYM-type 1 -3.28618
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.25077
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.22687
RUVBL1 RuvB-like AAA ATPase 1 -3.22491
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.20819
ELOVL6 ELOVL fatty acid elongase 6 -3.19295
NNT nicotinamide nucleotide transhydrogenase -3.1916
HDAC2 histone deacetylase 2 -3.18799
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -3.18106
AUH AU RNA binding protein/enoyl-CoA hydratase -3.17917
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -3.16981
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -3.16103
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.15362
GLOD4 glyoxalase domain containing 4 -3.1404
TTC19 tetratricopeptide repeat domain 19 -3.13456
FKTN fukutin -3.133
SHPK sedoheptulokinase -3.12894
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -3.12356
KIF20A kinesin family member 20A -3.12091
ANGPT1 angiopoietin 1 -3.11595
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.10021
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.09767
SH3D19 SH3 domain containing 19 -3.09578
FOXJ1 forkhead box J1 -3.09023
PSIP1 PC4 and SFRS1 interacting protein 1 -3.07062
FAM20B family with sequence similarity 20, member B -3.0669
CHL1 cell adhesion molecule L1-like -3.05887
CRTAP cartilage associated protein -3.05845
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.04225
ACOD1 aconitate decarboxylase 1 -3.02644
KIF4A kinesin family member 4A -3.01658
TMEM231 transmembrane protein 231 -3.0087
TFB1M transcription factor B1, mitochondrial -3.00354
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.99719
CRYL1 crystallin, lambda 1 -2.99267
XPC xeroderma pigmentosum, complementation group C -2.99257
CDK1 cyclin-dependent kinase 1 -2.9917
RMI1 RecQ mediated genome instability 1 -2.98664
GLI3 GLI family zinc finger 3 -2.97764
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.97685
NISCH nischarin -2.97487
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.97048
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.96717
KIF14 kinesin family member 14 -2.9622
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.95602
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.95124
KIAA0586 KIAA0586 -2.94246
COMMD10 COMM domain containing 10 -2.93905
NT5DC2 5'-nucleotidase domain containing 2 -2.93435
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.93384
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.92794
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.92521
TXNRD3 thioredoxin reductase 3 -2.92138
TSC22D3 TSC22 domain family, member 3 -2.90374
GTPBP8 GTP-binding protein 8 (putative) -2.89567
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.89362
CETN3 centrin, EF-hand protein, 3 -2.89131
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.88119
CDCA4 cell division cycle associated 4 -2.86604
NAT10 N-acetyltransferase 10 (GCN5-related) -2.85053
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.8496
VRK1 vaccinia related kinase 1 -2.84796
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.83708
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.83273
MDH1 malate dehydrogenase 1, NAD (soluble) -2.82854
CAVIN2 caveolae associated protein 2 -2.82267
CAMKMT calmodulin-lysine N-methyltransferase -2.81582
CREG1 cellular repressor of E1A-stimulated genes 1 -2.81423
PDHB pyruvate dehydrogenase (lipoamide) beta -2.81353
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.81062
DEXI Dexi homolog (mouse) -2.80656
DNAAF2 dynein, axonemal, assembly factor 2 -2.80275
FADS2 fatty acid desaturase 2 -2.79886
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.79806
MRPS16 mitochondrial ribosomal protein S16 -2.79795
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.79658
ANGEL1 angel homolog 1 (Drosophila) -2.7913
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.78727
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.78599
MICU2 mitochondrial calcium uptake 2 -2.78059
PUM2 pumilio RNA-binding family member 2 -2.77574
EXTL2 exostosin-like glycosyltransferase 2 -2.77417
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.77272
GEMIN2 gem (nuclear organelle) associated protein 2 -2.77104
GRHL2 grainyhead-like 2 (Drosophila) -2.77097
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.77064
SP8 Sp8 transcription factor -2.76695
TMEM168 transmembrane protein 168 -2.76219
PYGL phosphorylase, glycogen, liver -2.75104
ABHD14A abhydrolase domain containing 14A -2.74931
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.74082
C2CD5 C2 calcium-dependent domain containing 5 -2.73972
PEX3 peroxisomal biogenesis factor 3 -2.72475
PFKM phosphofructokinase, muscle -2.72379
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.72172
TRAPPC2L trafficking protein particle complex 2-like -2.72157
SCAP SREBF chaperone -2.71297
PLK1 polo-like kinase 1 -2.70873
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.70331
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.70265
DEPDC1 DEP domain containing 1 -2.7025
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.69798
TSKU tsukushi, small leucine rich proteoglycan -2.69723
THAP11 THAP domain containing 11 -2.69395
PCCA propionyl CoA carboxylase, alpha polypeptide -2.6883
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.68794
ANKRD10 ankyrin repeat domain 10 -2.68294
SPAG7 sperm associated antigen 7 -2.6819
PRR7 proline rich 7 (synaptic) -2.68041
NCAPD3 non-SMC condensin II complex, subunit D3 -2.68024
MIS18A MIS18 kinetochore protein A -2.67942
LARS1 leucyl-tRNA synthetase 1 -2.67571
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.67547
MAT2B methionine adenosyltransferase II, beta -2.67493
TMEM126B transmembrane protein 126B -2.67181
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -2.67018
ZMYM3 zinc finger, MYM-type 3 -2.66612
CZIB CXXC motif containing zinc binding protein -2.66388
CKAP2 cytoskeleton associated protein 2 -2.65889
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.65883
COQ3 coenzyme Q3 methyltransferase -2.65802
THOC7 THO complex 7 -2.65509
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.6528
COASY CoA synthase -2.64464
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.64329
ATP5PO ATP synthase peripheral stalk subunit OSCP -2.63657
TBC1D16 TBC1 domain family, member 16 -2.62894
ANKRD17 ankyrin repeat domain 17 -2.61629
DERA deoxyribose-phosphate aldolase (putative) -2.61409
BBOF1 basal body orientation factor 1 -2.60775
MTARC1 mitochondrial amidoxime reducing component 1 -2.60666
PRPF4 pre-mRNA processing factor 4 -2.60319
RIDA reactive intermediate imine deaminase A homolog -2.60215
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.59528
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.59514
ARB2A ARB2 cotranscriptional regulator A -2.5922
SPA17 sperm autoantigenic protein 17 -2.58533
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.57618
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.57375
SREBF2 sterol regulatory element binding transcription factor 2 -2.57332
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.5699
MRPL19 mitochondrial ribosomal protein L19 -2.56214
CLUH clustered mitochondria (cluA/CLU1) homolog -2.55618
MECR mitochondrial trans-2-enoyl-CoA reductase -2.55459
MOCS2 molybdenum cofactor synthesis 2 -2.55262
SNUPN snurportin 1 -2.54464
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.53266
ZNHIT3 zinc finger, HIT-type containing 3 -2.53259
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.53214
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.52958
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -2.52611
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.52603
IFRD2 interferon-related developmental regulator 2 -2.52377
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.52352
ATP5F1D ATP synthase F1 subunit delta -2.5232
COL1A2 collagen, type I, alpha 2 -2.5184
HYAL2 hyaluronoglucosaminidase 2 -2.51804
APRT adenine phosphoribosyltransferase -2.51483
CCDC51 coiled-coil domain containing 51 -2.51439
TACC3 transforming, acidic coiled-coil containing protein 3 -2.51252
ACY1 aminoacylase 1 -2.51008
TRMT61B tRNA methyltransferase 61B -2.50021
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.49931
SLIRP SRA stem-loop interacting RNA binding protein -2.49673
MRPL3 mitochondrial ribosomal protein L3 -2.49198
TRIP13 thyroid hormone receptor interactor 13 -2.48982
PEX12 peroxisomal biogenesis factor 12 -2.48766
MRPL12 mitochondrial ribosomal protein L12 -2.4822
SKIC8 SKI8 subunit of superkiller complex -2.47971
TMEM43 transmembrane protein 43 -2.47512
ETFB electron-transfer-flavoprotein, beta polypeptide -2.47407
MRNIP MRN complex interacting protein -2.47147
POGK pogo transposable element with KRAB domain -2.47052
SYPL1 synaptophysin-like 1 -2.46326
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.46312
MRS2 MRS2 magnesium transporter -2.46048
ELP4 elongator acetyltransferase complex subunit 4 -2.45884
ASF1A anti-silencing function 1A histone chaperone -2.45521
GLRX5 glutaredoxin 5 -2.45367
MRPL39 mitochondrial ribosomal protein L39 -2.45324
COMMD8 COMM domain containing 8 -2.4502
TIPRL TOR signaling pathway regulator -2.44563
CBR4 carbonyl reductase 4 -2.44413
DNM1 dynamin 1 -2.43734
CCNG1 cyclin G1 -2.43587
RAB20 RAB20, member RAS oncogene family -2.43378
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.42961
CASC3 cancer susceptibility candidate 3 -2.42923
CYFIP1 cytoplasmic FMR1 interacting protein 1 -2.42709
PRPF8 pre-mRNA processing factor 8 -2.42409
LYPLA1 lysophospholipase I -2.4167
LAGE3 L antigen family, member 3 -2.4166
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.41572
ZNF451 zinc finger protein 451 -2.41385
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.41333
RCAN2 regulator of calcineurin 2 -2.41239
DHCR7 7-dehydrocholesterol reductase -2.40767
KYAT1 kynurenine aminotransferase 1 -2.40078
INTS14 integrator complex subunit 14 -2.39971
DBF4 DBF4 zinc finger -2.39849
ICE2 interactor of little elongation complex ELL subunit 2 -2.39495
SPPL2A signal peptide peptidase like 2A -2.39089
PRKX protein kinase, X-linked -2.38652
BSPRY B-box and SPRY domain containing -2.3826
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.38204
SCML2 sex comb on midleg-like 2 (Drosophila) -2.38111
DEAF1 DEAF1 transcription factor -2.3811
PEX11A peroxisomal biogenesis factor 11 alpha -2.37845
HMGB2 high mobility group box 2 -2.37625
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.37576
THTPA thiamine triphosphatase -2.37399
ATRAID all-trans retinoic acid-induced differentiation factor -2.37188
SPTSSA serine palmitoyltransferase, small subunit A -2.36986
CENPS-CORT CENPS-CORT readthrough -2.3648
ZNF76 zinc finger protein 76 -2.35925
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.35687
DET1 de-etiolated homolog 1 (Arabidopsis) -2.35549
ADGRB3 adhesion G protein-coupled receptor B3 -2.35329
SRP9 signal recognition particle 9kDa -2.35236
POGLUT1 protein O-glucosyltransferase 1 -2.35044
C1GALT1C1 C1GALT1-specific chaperone 1 -2.34926
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.34862
SATB1 SATB homeobox 1 -2.33992
CAPN15 calpain 15 -2.33932
CTSO cathepsin O -2.33858
PROS1 protein S (alpha) -2.33672
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.33647
CDKN3 cyclin-dependent kinase inhibitor 3 -2.3321
DMAC2L distal membrane arm assembly component 2 like -2.33111
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.32186
TMT1A thiol methyltransferase 1A -2.32132
SEC23A Sec23 homolog A (S. cerevisiae) -2.32104
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.31878
LOC112694756 uncharaterized LOC112694756 -2.31731
ESD esterase D -2.31398
CCDC25 coiled-coil domain containing 25 -2.31371
AMT aminomethyltransferase -2.31209
MRPS27 mitochondrial ribosomal protein S27 -2.31044
OSBPL8 oxysterol binding protein-like 8 -2.30886
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.30209
TROAP trophinin associated protein -2.3011
PFN2 profilin 2 -2.29413
BTBD1 BTB (POZ) domain containing 1 -2.28162
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.27632
FASN fatty acid synthase -2.27588
ETV1 ets variant 1 -2.27586
SMC1A structural maintenance of chromosomes 1A -2.27162
KDM1A lysine (K)-specific demethylase 1A -2.27121
PLP1 proteolipid protein 1 -2.27049
DOCK1 dedicator of cytokinesis 1 -2.26939
NPM3 nucleophosmin/nucleoplasmin 3 -2.26881
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.26863
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.26857
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.26697
SELENOF selenoprotein F -2.26598
CCNF cyclin F -2.26076
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.25996
IPO4 importin 4 -2.25916
XPO1 exportin 1 -2.259
CAAP1 caspase activity and apoptosis inhibitor 1 -2.25666
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.25005
FHL5 four and a half LIM domains 5 -2.24817
HSDL2 hydroxysteroid dehydrogenase like 2 -2.24788
GAA glucosidase, alpha; acid -2.2456
BTN3A1 butyrophilin, subfamily 3, member A1 -2.24337
COX11 COX11 cytochrome c oxidase copper chaperone -2.24261
TYR tyrosinase -2.24095
FASTKD3 FAST kinase domains 3 -2.24087
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.23876
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.23718
EPS15 epidermal growth factor receptor pathway substrate 15 -2.23632
MSL1 male-specific lethal 1 homolog (Drosophila) -2.23035
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.22911
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.22856
ANAPC1 anaphase promoting complex subunit 1 -2.22492
IPO9 importin 9 -2.22173
TXNDC9 thioredoxin domain containing 9 -2.22088
NLRP4 NLR family, pyrin domain containing 4 -2.21824
ASPA aspartoacylase -2.21702
TMEM186 transmembrane protein 186 -2.21633
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.21544
GALE UDP-galactose-4-epimerase -2.21495
CGREF1 cell growth regulator with EF-hand domain 1 -2.21473
THEM6 thioesterase superfamily member 6 -2.21441
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.20267
MYCBP MYC binding protein -2.20188
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -2.20004
GFUS GDP-L-fucose synthase -2.19994
SUOX sulfite oxidase -2.19887
ENOSF1 enolase superfamily member 1 -2.19866
TM2D1 TM2 domain containing 1 -2.19371
CIC capicua transcriptional repressor -2.19113
MCM3 minichromosome maintenance complex component 3 -2.19096
UBL3 ubiquitin-like 3 -2.18662
SKP1 S-phase kinase-associated protein 1 -2.18443
TMEM209 transmembrane protein 209 -2.18292
PRKCD protein kinase C, delta -2.1803
FZD4 frizzled class receptor 4 -2.18025
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.17825
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.1761
ACSL5 acyl-CoA synthetase long-chain family member 5 -2.17441
DNAAF5 dynein, axonemal, assembly factor 5 -2.17277
RSU1 Ras suppressor protein 1 -2.17263
TBC1D5 TBC1 domain family, member 5 -2.17147
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -2.16928
TMEM177 transmembrane protein 177 -2.16812
NUP37 nucleoporin 37kDa -2.16705
MRPL17 mitochondrial ribosomal protein L17 -2.16424
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.15957
FUCA1 fucosidase, alpha-L- 1, tissue -2.15885
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.15852
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.15684
PTCD3 pentatricopeptide repeat domain 3 -2.15667
CENPA centromere protein A -2.15098
ATF5 activating transcription factor 5 -2.14786
ADNP activity-dependent neuroprotector homeobox -2.14765
MCF2L MCF.2 cell line derived transforming sequence-like -2.14654
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.14619
SOAT2 sterol O-acyltransferase 2 -2.14569
SH3YL1 SH3 and SYLF domain containing 1 -2.14496
ICMT isoprenylcysteine carboxyl methyltransferase -2.1441
SUB1 SUB1 homolog (S. cerevisiae) -2.143
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.14253
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.14181
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -2.14134
MPZL2 myelin protein zero-like 2 -2.14131
ZFYVE21 zinc finger, FYVE domain containing 21 -2.14039
STK11 serine/threonine kinase 11 -2.13792
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.1374
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.13736
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.13338
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.13108
FASTKD1 FAST kinase domains 1 -2.12762
MRPL34 mitochondrial ribosomal protein L34 -2.12761
STEAP3 STEAP family member 3, metalloreductase -2.12589
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.12456
GOLGA8A golgin A8 family, member A -2.12064
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.1203
AFG3L2 AFG3-like AAA ATPase 2 -2.11983
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.11841
SCARB1 scavenger receptor class B, member 1 -2.11601
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.11283
LIPT1 lipoyltransferase 1 -2.11258
R3HDM2 R3H domain containing 2 -2.11253
HMGN4 high mobility group nucleosomal binding domain 4 -2.1088
NPDC1 neural proliferation, differentiation and control, 1 -2.10663
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.10611
BAHCC1 BAH domain and coiled-coil containing 1 -2.10567
LRRC40 leucine rich repeat containing 40 -2.10502
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.10352
FBXO3 F-box protein 3 -2.1035
ZC3H4 zinc finger CCCH-type containing 4 -2.09149
RBMX RNA binding motif protein, X-linked -2.09116
HLTF helicase-like transcription factor -2.08841
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.08668
TNS2 tensin 2 -2.08626
WDR12 WD repeat domain 12 -2.0857
PIMREG PICALM interacting mitotic regulator -2.08563
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.08463
MRPL42 mitochondrial ribosomal protein L42 -2.08321
LRRC17 leucine rich repeat containing 17 -2.08295
PCGF2 polycomb group ring finger 2 -2.08245
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.08138
PCYOX1 prenylcysteine oxidase 1 -2.08029
DPY19L4 dpy-19-like 4 (C. elegans) -2.08018
GPSM2 G-protein signaling modulator 2 -2.07896
MSRA methionine sulfoxide reductase A -2.07715
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -2.07667
SETD1B SET domain containing 1B -2.07299
ST20-MTHFS ST20-MTHFS readthrough -2.07288
AK4 adenylate kinase 4 -2.07225
ISOC1 isochorismatase domain containing 1 -2.07219
TMPRSS11D transmembrane protease, serine 11D -2.0718
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.0705
PAIP1 poly(A) binding protein interacting protein 1 -2.07007
PGAM4 phosphoglycerate mutase family member 4 -2.06988
HMGB1 high mobility group box 1 -2.06979
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.06967
IFT81 intraflagellar transport 81 -2.06937
KRCC1 lysine-rich coiled-coil 1 -2.06779
TMEM267 transmembrane protein 267 -2.06665
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.06663
SIRT3 sirtuin 3 -2.06602
PARP16 poly (ADP-ribose) polymerase family, member 16 -2.0651
PRUNE1 prune exopolyphosphatase 1 -2.0642
METTL18 methyltransferase like 18 -2.05794
SKIC2 SKI2 subunit of superkiller complex -2.05783
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.05749
ZXDC ZXD family zinc finger C -2.05694
APEH acylaminoacyl-peptide hydrolase -2.05146
RWDD1 RWD domain containing 1 -2.05136
ELP5 elongator acetyltransferase complex subunit 5 -2.05004
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.04831
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.04828
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.04664
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -2.04033
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.03751
ACYP2 acylphosphatase 2, muscle type -2.03739
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.03736
HMGB3 high mobility group box 3 -2.03564
SP3 Sp3 transcription factor -2.03428
MAB21L4 mab-21 like 4 -2.03273
CIDEB cell death-inducing DFFA-like effector b -2.03229
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.03134
CDC25B cell division cycle 25B -2.02975
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.02587
APIP APAF1 interacting protein -2.02476
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.02279
S100A3 S100 calcium binding protein A3 -2.02249
PMF1-BGLAP PMF1-BGLAP readthrough -2.0223
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.02226
TP53RK TP53 regulating kinase -2.02043
FAM234B family with sequence similarity 234 member B -2.01709
EVL Enah/Vasp-like -2.01657
PITX1 paired-like homeodomain 1 -2.01481
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.01452
PCNP PEST proteolytic signal containing nuclear protein -2.0141
RWDD2B RWD domain containing 2B -2.01201
DCTD dCMP deaminase -2.01181
MRPL35 mitochondrial ribosomal protein L35 -2.01059
PRC1 protein regulator of cytokinesis 1 -2.00703
IFITM3 interferon induced transmembrane protein 3 -2.00351
DEK DEK proto-oncogene -2.00284
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.00153
BTBD2 BTB (POZ) domain containing 2 -2.00039