CRCGN016_MCF10A.WT.HP_24H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloropropane 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.15634
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.26087
ZMIZ1 zinc finger, MIZ-type containing 1 2.88803
OLFML2B olfactomedin-like 2B 2.53937
MCUR1 mitochondrial calcium uniporter regulator 1 2.37258
AGR2 anterior gradient 2 2.33126
IGHMBP2 immunoglobulin mu binding protein 2 2.30978
SPA17 sperm autoantigenic protein 17 2.28363
TTC12 tetratricopeptide repeat domain 12 2.11459
COMP cartilage oligomeric matrix protein 2.09664

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -6.61003
GDF15 growth differentiation factor 15 -6.54653
HMG20B high mobility group 20B -6.10677
ISOC1 isochorismatase domain containing 1 -4.6707
CHMP4B charged multivesicular body protein 4B -4.54964
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.05356
TIMP1 TIMP metallopeptidase inhibitor 1 -3.89106
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.90876
HEATR1 HEAT repeat containing 1 -2.90279
KRT14 keratin 14, type I -2.80031
SGK1 serum/glucocorticoid regulated kinase 1 -2.66041
TTC17 tetratricopeptide repeat domain 17 -2.44358
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -2.31535
CACTIN cactin, spliceosome C complex subunit -2.24578
LMO3 LIM domain only 3 (rhombotin-like 2) -2.12487
MTERF3 mitochondrial transcription termination factor 3 -2.10643
HBE1 hemoglobin, epsilon 1 -2.09394
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.08208
HMOX2 heme oxygenase 2 -2.05165
S100A8 S100 calcium binding protein A8 -2.01259
HTRA1 HtrA serine peptidase 1 -2.00012