CRCGN016_MCF10A.WT.HP_24H:L17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloropropane 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

28 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 6.64466
ACAA1 acetyl-CoA acyltransferase 1 5.24258
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.8889
COMP cartilage oligomeric matrix protein 3.75936
NRBF2 nuclear receptor binding factor 2 2.5477
MCUR1 mitochondrial calcium uniporter regulator 1 2.48388
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.36579
GGCT gamma-glutamylcyclotransferase 2.2747
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.2681
TSLIG3A tRNA splicing ligase complex subunit 3A 2.19777
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.06115
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.05888
SESN1 sestrin 1 2.01556
ANXA6 annexin A6 2.01246
TCEAL4 transcription elongation factor A (SII)-like 4 2.01019

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -4.35083
HEATR1 HEAT repeat containing 1 -4.03189
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.5652
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -3.02894
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.83119
SGK1 serum/glucocorticoid regulated kinase 1 -2.66345
TENT4A terminal nucleotidyltransferase 4A -2.57736
ARID4B AT rich interactive domain 4B (RBP1-like) -2.19273
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -2.19079
TRIB3 tribbles pseudokinase 3 -2.14008
SPEG SPEG complex locus -2.0657
NHEJ1 nonhomologous end-joining factor 1 -2.04965
BRME1 break repair meiotic recombinase recruitment factor 1 -2.00678