CRCGN016_MCF10A.WT.HP_24H:M02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofurantoin 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 3.96017
AGR2 anterior gradient 2 3.21643
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.99247
GRB10 growth factor receptor-bound protein 10 2.86647
STIMATE STIM activating enhancer 2.85373
ACAA1 acetyl-CoA acyltransferase 1 2.49256
ZNF184 zinc finger protein 184 2.36443
ICOS inducible T-cell co-stimulator 2.32132
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.29996
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.26959
FAM184A family with sequence similarity 184, member A 2.26453
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.24634
PDIA5 protein disulfide isomerase family A, member 5 2.22078
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.1874
SOD1 superoxide dismutase 1, soluble 2.04792

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -8.11143
ZMIZ1 zinc finger, MIZ-type containing 1 -4.14772
MELK maternal embryonic leucine zipper kinase -4.05708
YME1L1 YME1-like 1 ATPase -4.00967
MAPK13 mitogen-activated protein kinase 13 -3.90354
VAT1 vesicle amine transport 1 -3.89012
RNF167 ring finger protein 167 -3.60405
CD58 CD58 molecule -3.46076
LYPLA1 lysophospholipase I -3.39383
DNM1L dynamin 1-like -3.36095
TXNDC9 thioredoxin domain containing 9 -3.04527
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.88415
UBE3C ubiquitin protein ligase E3C -2.80762
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.72022
GNPAT glyceronephosphate O-acyltransferase -2.4134
WAC WW domain containing adaptor with coiled-coil -2.35577
PGBD5 piggyBac transposable element derived 5 -2.23366
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.12866
LGALS1 lectin, galactoside-binding, soluble, 1 -2.09611
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.09158
SMC6 structural maintenance of chromosomes 6 -2.06395
MRPL15 mitochondrial ribosomal protein L15 -2.06281