CRCGN016_MCF10A.WT.HP_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofurantoin 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 4.7477
HMOX1 heme oxygenase 1 4.4457
CNRIP1 cannabinoid receptor interacting protein 1 4.34426
AGR2 anterior gradient 2 3.20025
STIMATE STIM activating enhancer 2.99494
STAMBP STAM binding protein 2.57824
CGRRF1 cell growth regulator with ring finger domain 1 2.56564
WIF1 WNT inhibitory factor 1 2.52277
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.46485
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.19033
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.18201
FBXL12 F-box and leucine-rich repeat protein 12 2.16791
RNF113A ring finger protein 113A 2.03497
CENPU centromere protein U 2.03162
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.02504

decreased expression

Symbol Name Standardized Value
DCK deoxycytidine kinase -8.5393
KIF14 kinesin family member 14 -4.77009
ZDHHC6 zinc finger, DHHC-type containing 6 -4.47547
BASP1 brain abundant, membrane attached signal protein 1 -3.63071
RTN2 reticulon 2 -3.46401
ARID4B AT rich interactive domain 4B (RBP1-like) -3.23264
IFRD2 interferon-related developmental regulator 2 -3.04054
TMEM115 transmembrane protein 115 -2.99724
CANT1 calcium activated nucleotidase 1 -2.91038
GDF15 growth differentiation factor 15 -2.84322
MTERF3 mitochondrial transcription termination factor 3 -2.75973
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.47799
HTRA1 HtrA serine peptidase 1 -2.439
SFMBT1 Scm-like with four mbt domains 1 -2.22143
MSN moesin -2.1002
FPGS folylpolyglutamate synthase -2.09993
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.08799
TUSC2 tumor suppressor candidate 2 -2.05189