CRCGN016_MCF10A.WT.HP_24H:M04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bis(chloromethyl) ether 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 5.53156
AGR2 anterior gradient 2 5.38959
SNAP25 synaptosomal-associated protein, 25kDa 4.58296
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.0783
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.84305
GRB10 growth factor receptor-bound protein 10 2.77099
HARS1 histidyl-tRNA synthetase 1 2.36092
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.26388

decreased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 -8.53059
GDF15 growth differentiation factor 15 -4.51371
CHIC2 cysteine-rich hydrophobic domain 2 -4.49031
C2CD5 C2 calcium-dependent domain containing 5 -4.41691
MT1X metallothionein 1X -3.99524
TM9SF3 transmembrane 9 superfamily member 3 -3.55126
PCCB propionyl CoA carboxylase, beta polypeptide -3.30762
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.07839
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.67382
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.6613
ANXA2 annexin A2 -2.47825
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.41942
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -2.39624
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.35671
EXOC1 exocyst complex component 1 -2.34157
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -2.25463
NCAPD2 non-SMC condensin I complex, subunit D2 -2.22328
SAA4 serum amyloid A4, constitutive -2.10768
PRSS53 protease, serine, 53 -2.1022
CD1B CD1b molecule -2.05029
CD33 CD33 molecule -2.04465