CRCGN016_MCF10A.WT.HP_24H:M06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bis(chloromethyl) ether 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.23107
HBA1 hemoglobin, alpha 1 3.93612
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 3.48863
COMP cartilage oligomeric matrix protein 3.33333
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.21587
SPAG4 sperm associated antigen 4 3.18423
WIF1 WNT inhibitory factor 1 2.6647
KCTD5 potassium channel tetramerization domain containing 5 2.56153
HBB hemoglobin, beta 2.24638
UGDH UDP-glucose 6-dehydrogenase 2.21207
STX4 syntaxin 4 2.1409
GPC1 glypican 1 2.01423

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.28455
JMJD6 jumonji domain containing 6 -3.20167
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.11343
PCNA proliferating cell nuclear antigen -3.1085
HSPA8 heat shock 70kDa protein 8 -2.74536
OXA1L oxidase (cytochrome c) assembly 1-like -2.53173
RXYLT1 ribitol xylosyltransferase 1 -2.25983
SUSD6 sushi domain containing 6 -2.1983
KRT14 keratin 14, type I -2.15397