| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | beta testosterone 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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116 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.70686 |
| AGR2 | anterior gradient 2 | 3.92538 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.54948 |
| ZW10 | zw10 kinetochore protein | 3.5121 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 3.42051 |
| HBA1 | hemoglobin, alpha 1 | 3.31479 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.31179 |
| MAP7 | microtubule-associated protein 7 | 3.28114 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 3.0967 |
| SLC75A1 | solute carrier family 75 member 1 | 2.8918 |
| MSRA | methionine sulfoxide reductase A | 2.82741 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 2.81808 |
| RPN1 | ribophorin I | 2.75569 |
| STX1A | syntaxin 1A (brain) | 2.73324 |
| FAIM | Fas apoptotic inhibitory molecule | 2.66829 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 2.65445 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.64587 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.62329 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 2.5642 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.5307 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 2.46248 |
| TPD52L2 | tumor protein D52-like 2 | 2.441 |
| DUSP4 | dual specificity phosphatase 4 | 2.43952 |
| HMGA2 | high mobility group AT-hook 2 | 2.3784 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.29858 |
| MRPS10 | mitochondrial ribosomal protein S10 | 2.29164 |
| HAS2 | hyaluronan synthase 2 | 2.29086 |
| YIPF3 | Yip1 domain family, member 3 | 2.26963 |
| DUSP6 | dual specificity phosphatase 6 | 2.26823 |
| BFSP1 | beaded filament structural protein 1, filensin | 2.26708 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.26262 |
| CTRC | chymotrypsin C (caldecrin) | 2.25865 |
| GRM4 | glutamate receptor, metabotropic 4 | 2.24222 |
| BCORL1 | BCL6 corepressor-like 1 | 2.24082 |
| ANKRD11 | ankyrin repeat domain 11 | 2.23615 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.23539 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.23196 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.20141 |
| RAB40B | RAB40B, member RAS oncogene family | 2.18981 |
| GRB10 | growth factor receptor-bound protein 10 | 2.18674 |
| HBEGF | heparin-binding EGF-like growth factor | 2.18608 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.18102 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 2.16677 |
| SMAD3 | SMAD family member 3 | 2.15508 |
| GRAMD4 | GRAM domain containing 4 | 2.12859 |
| SQOR | sulfide quinone oxidoreductase | 2.12624 |
| CDCP1 | CUB domain containing protein 1 | 2.12105 |
| TUBB6 | tubulin, beta 6 class V | 2.11798 |
| DNAAF11 | dynein axonemal assembly factor 11 | 2.11732 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | 2.10384 |
| ARHGAP5 | Rho GTPase activating protein 5 | 2.1018 |
| PRKCQ | protein kinase C, theta | 2.08795 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 | 2.08329 |
| MOK | MOK protein kinase | 2.0668 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 2.04873 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | 2.04346 |
| KRT19 | keratin 19, type I | 2.03717 |
| FES | FES proto-oncogene, tyrosine kinase | 2.03011 |
| CTC1 | CTS telomere maintenance complex component 1 | 2.02255 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) | 2.01593 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.00846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMG20B | high mobility group 20B | -6.27515 |
| MSMO1 | methylsterol monooxygenase 1 | -5.72751 |
| HEATR1 | HEAT repeat containing 1 | -5.6912 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -5.68007 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -4.89292 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.94214 |
| TRAPPC3 | trafficking protein particle complex 3 | -3.83198 |
| TSC22D3 | TSC22 domain family, member 3 | -3.75559 |
| CCNB1 | cyclin B1 | -3.68697 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -3.46167 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.40717 |
| LDHD | lactate dehydrogenase D | -3.28 |
| HSPA8 | heat shock 70kDa protein 8 | -3.23918 |
| GDF15 | growth differentiation factor 15 | -3.09634 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.08772 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -3.00516 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.98227 |
| PRR15L | proline rich 15-like | -2.96792 |
| HAX1 | HCLS1 associated protein X-1 | -2.95964 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.82264 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.8152 |
| FHIT | fragile histidine triad | -2.61704 |
| MLYCD | malonyl-CoA decarboxylase | -2.60826 |
| ADRB2 | adrenoceptor beta 2, surface | -2.59307 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.56553 |
| MRPL34 | mitochondrial ribosomal protein L34 | -2.54527 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -2.46637 |
| INSIG1 | insulin induced gene 1 | -2.40929 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | -2.40786 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -2.39833 |
| ZMYM4 | zinc finger, MYM-type 4 | -2.34921 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -2.3016 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 | -2.28226 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.27386 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.26755 |
| TRIM37 | tripartite motif containing 37 | -2.25601 |
| TLK2 | tousled-like kinase 2 | -2.2548 |
| MT1X | metallothionein 1X | -2.2539 |
| ATG4A | autophagy related 4A, cysteine peptidase | -2.23797 |
| CDC42SE1 | CDC42 small effector 1 | -2.21094 |
| TMEM259 | transmembrane protein 259 | -2.1905 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -2.17681 |
| CYB561D2 | cytochrome b561 family, member D2 | -2.14959 |
| NCOA4 | nuclear receptor coactivator 4 | -2.11503 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | -2.10531 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -2.10048 |
| MTNAP1 | mitochondrial nucleoid associated protein 1 | -2.09788 |
| MRPL49 | mitochondrial ribosomal protein L49 | -2.06873 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.06645 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 | -2.06196 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -2.06185 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | -2.05766 |
| MDH1 | malate dehydrogenase 1, NAD (soluble) | -2.04317 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -2.0359 |
| BABAM1 | BRISC and BRCA1 A complex member 1 | -2.00549 |
