CRCGN016_MCF10A.WT.HP_24H:M08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta testosterone 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.67375
CHMP6 charged multivesicular body protein 6 3.82379
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.67618
OLFML2B olfactomedin-like 2B 3.53125
CDCA4 cell division cycle associated 4 3.51917
WFS1 Wolfram syndrome 1 (wolframin) 3.04323
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.61836
CHN1 chimerin 1 2.37222
KDM5A lysine (K)-specific demethylase 5A 2.33526
MAP7 microtubule-associated protein 7 2.31654
PCNA proliferating cell nuclear antigen 2.2594
HOXA10 homeobox A10 2.14248
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.08106
COMP cartilage oligomeric matrix protein 2.04283

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -6.37247
BASP1 brain abundant, membrane attached signal protein 1 -5.58051
CDC20 cell division cycle 20 -3.69043
ISOC1 isochorismatase domain containing 1 -3.35795
CD58 CD58 molecule -3.06189
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.76044
MELK maternal embryonic leucine zipper kinase -2.72653
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -2.60444
CSRP1 cysteine and glycine-rich protein 1 -2.53833
GDF15 growth differentiation factor 15 -2.50003
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -2.33816
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.25383
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.228
SLAMF1 signaling lymphocytic activation molecule family member 1 -2.18026
ARID4B AT rich interactive domain 4B (RBP1-like) -2.17858
RAB1B RAB1B, member RAS oncogene family -2.10714
PFN1 profilin 1 -2.06392
SLC12A8 solute carrier family 12, member 8 -2.06066
RNF208 ring finger protein 208 -2.0401
DPP6 dipeptidyl-peptidase 6 -2.01733
FAIM Fas apoptotic inhibitory molecule -2.00441