CRCGN016_MCF10A.WT.HP_24H:M10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibromomannitol 99.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 4.99304
SPAG4 sperm associated antigen 4 4.30968
PPARG peroxisome proliferator-activated receptor gamma 4.26632
COMP cartilage oligomeric matrix protein 3.26064
KIF5C kinesin family member 5C 3.14449
IGHMBP2 immunoglobulin mu binding protein 2 2.92075
MMP1 matrix metallopeptidase 1 2.45124
NCK1 NCK adaptor protein 1 2.27256
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.2161
CNRIP1 cannabinoid receptor interacting protein 1 2.20704
TBPL1 TBP-like 1 2.12129
PCID2 PCI domain containing 2 2.01164

decreased expression

Symbol Name Standardized Value
FOS FBJ murine osteosarcoma viral oncogene homolog -7.3409
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -5.29457
HMG20B high mobility group 20B -4.75531
ISOC1 isochorismatase domain containing 1 -4.69219
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.61512
DSG2 desmoglein 2 -4.41395
CDK4 cyclin-dependent kinase 4 -4.23572
EPN2 epsin 2 -4.02352
CORO1A coronin, actin binding protein, 1A -3.80382
CDPF1 cysteine-rich, DPF motif domain containing 1 -3.20029
PFN1 profilin 1 -2.93527
PTK2 protein tyrosine kinase 2 -2.56178
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.46949
MSN moesin -2.41093
MFSD12 major facilitator superfamily domain containing 12 -2.33343
TLE5 TLE family member 5, transcriptional modulator -2.15322