CRCGN016_MCF10A.WT.HP_24H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibromomannitol 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.68811
COMP cartilage oligomeric matrix protein 3.9987
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.55462
ACAA1 acetyl-CoA acyltransferase 1 3.19999
ADAM10 ADAM metallopeptidase domain 10 3.14746
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.07793
MAST2 microtubule associated serine/threonine kinase 2 2.73945
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.51959
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.45239
CNRIP1 cannabinoid receptor interacting protein 1 2.25173
CGRRF1 cell growth regulator with ring finger domain 1 2.16924
HMOX1 heme oxygenase 1 2.04866
URGCP upregulator of cell proliferation 2.03583
CCL2 chemokine (C-C motif) ligand 2 2.00716

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -4.88126
HMG20B high mobility group 20B -4.47192
GDF15 growth differentiation factor 15 -4.45507
BASP1 brain abundant, membrane attached signal protein 1 -3.82453
ARID4B AT rich interactive domain 4B (RBP1-like) -2.83658
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.44078
CBR3 carbonyl reductase 3 -2.34963
RAI14 retinoic acid induced 14 -2.27367