CRCGN016_MCF10A.WT.HP_24H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(b)fluoranthene 98.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GRB10 growth factor receptor-bound protein 10 3.96682
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.46196
IL1B interleukin 1, beta 2.33565
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.23592
HBA1 hemoglobin, alpha 1 2.22495
RPP38 ribonuclease P/MRP 38kDa subunit 2.20189
EDN1 endothelin 1 2.16382
CGRRF1 cell growth regulator with ring finger domain 1 2.16341
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.08158
PLSCR3 phospholipid scramblase 3 2.06202

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -5.15308
BASP1 brain abundant, membrane attached signal protein 1 -4.4215
NPDC1 neural proliferation, differentiation and control, 1 -4.40709
STXBP2 syntaxin binding protein 2 -3.04909
GDF15 growth differentiation factor 15 -2.90312
DUSP14 dual specificity phosphatase 14 -2.90102
CANT1 calcium activated nucleotidase 1 -2.25788