CRCGN016_MCF10A.WT.HP_24H:M14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(b)fluoranthene 32.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

45 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 8.5577
CXCL2 chemokine (C-X-C motif) ligand 2 5.25085
AGR2 anterior gradient 2 5.03245
CDCA4 cell division cycle associated 4 4.86396
CXCL3 chemokine (C-X-C motif) ligand 3 3.85659
FGFR4 fibroblast growth factor receptor 4 3.807
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.74621
EPHB2 EPH receptor B2 3.73077
COMP cartilage oligomeric matrix protein 3.5239
RTN2 reticulon 2 3.5115
GRB10 growth factor receptor-bound protein 10 3.26584
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.9071
HBA1 hemoglobin, alpha 1 2.7321
GPATCH8 G patch domain containing 8 2.439
WIF1 WNT inhibitory factor 1 2.42013
CLBA1 clathrin binding box of aftiphilin containing 1 2.37472
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.31281
MYL11 myosin light chain 11 2.28626
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.27373
IGF2 insulin-like growth factor 2 2.27258
TNNT3 troponin T type 3 (skeletal, fast) 2.2365
CCNE1 cyclin E1 2.1468
FERMT1 fermitin family member 1 2.11723
GPX2 glutathione peroxidase 2 2.11023
HRC histidine rich calcium binding protein 2.06583
NUCB2 nucleobindin 2 2.05538
IL13 interleukin 13 2.05357
UNC13D unc-13 homolog D (C. elegans) 2.03316
FANCE Fanconi anemia, complementation group E 2.01304
ACTA2 actin, alpha 2, smooth muscle, aorta 2.00482
MMP23B matrix metallopeptidase 23B 2.00232

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -5.50972
HMG20B high mobility group 20B -4.98149
KRT14 keratin 14, type I -4.80045
HEATR1 HEAT repeat containing 1 -3.80243
PSIP1 PC4 and SFRS1 interacting protein 1 -3.42558
SGK1 serum/glucocorticoid regulated kinase 1 -3.04434
SPRED2 sprouty-related, EVH1 domain containing 2 -2.96432
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.48567
MT1X metallothionein 1X -2.40255
ANXA2 annexin A2 -2.25286
CSRP1 cysteine and glycine-rich protein 1 -2.1274
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -2.0289
MLF2 myeloid leukemia factor 2 -2.01803
NLGN1 neuroligin 1 -2.00223