CRCGN016_MCF10A.WT.HP_24H:M19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ITE 102.69 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 3.10867
HDGFL3 HDGF like 3 2.90804
ADGRE5 adhesion G protein-coupled receptor E5 2.70791
CXCR4 chemokine (C-X-C motif) receptor 4 2.67346
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.66065
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.61861
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.56583
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.45533
WASF3 WAS protein family, member 3 2.27099
KDM5A lysine (K)-specific demethylase 5A 2.14043
FAIM Fas apoptotic inhibitory molecule 2.12586
ABHD4 abhydrolase domain containing 4 2.11816
FSD1 fibronectin type III and SPRY domain containing 1 2.04366
IL1B interleukin 1, beta 2.01375

decreased expression

Symbol Name Standardized Value
NLRP4 NLR family, pyrin domain containing 4 -4.3382
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.90753
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.86926
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.72848
CCNB2 cyclin B2 -3.29018
KIF14 kinesin family member 14 -3.25872
SCYL3 SCY1-like 3 (S. cerevisiae) -2.96983
HMG20B high mobility group 20B -2.82644
BASP1 brain abundant, membrane attached signal protein 1 -2.78164
RALGDS ral guanine nucleotide dissociation stimulator -2.67108
MELK maternal embryonic leucine zipper kinase -2.43883
COL18A1 collagen, type XVIII, alpha 1 -2.05502