CRCGN016_MCF10A.WT.HP_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ITE 34.23 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.11379
HBA1 hemoglobin, alpha 1 3.95676
SSBP2 single-stranded DNA binding protein 2 3.35559
FKBP14 FK506 binding protein 14, 22 kDa 3.34378
FGFR4 fibroblast growth factor receptor 4 3.15757
CCNA1 cyclin A1 3.00169
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.79208
IL1B interleukin 1, beta 2.67128
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.3489
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.31207
SMAD3 SMAD family member 3 2.25052
GPATCH8 G patch domain containing 8 2.17947
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.01177

decreased expression

Symbol Name Standardized Value
DSG2 desmoglein 2 -4.03286
DNM1L dynamin 1-like -3.62158
SGK1 serum/glucocorticoid regulated kinase 1 -3.24615
GDF15 growth differentiation factor 15 -3.14584
UFM1 ubiquitin-fold modifier 1 -2.97787
BAD BCL2-associated agonist of cell death -2.9613
KRT14 keratin 14, type I -2.86682
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.68198
TENT4A terminal nucleotidyltransferase 4A -2.447
OXA1L oxidase (cytochrome c) assembly 1-like -2.31535
MYO9A myosin IXA -2.28329
IQSEC2 IQ motif and Sec7 domain 2 -2.25314
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -2.13022
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.12966
IRX4 iroquois homeobox 4 -2.06793
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.04479