CRCGN016_MCF10A.WT.HP_24H:M21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ITE 11.41 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 5.54106
HBA1 hemoglobin, alpha 1 4.35846
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.1218
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.11722
AGR2 anterior gradient 2 2.99467
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.599
EVL Enah/Vasp-like 2.52674
TSPYL5 TSPY-like 5 2.03315
SOCS3 suppressor of cytokine signaling 3 2.01068
IL1B interleukin 1, beta 2.00957

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -7.25759
HMG20B high mobility group 20B -5.33655
SLC35F2 solute carrier family 35, member F2 -5.32569
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.85446
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -3.57964
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.49338
RXYLT1 ribitol xylosyltransferase 1 -2.85645
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.67996
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.57522
ZDHHC6 zinc finger, DHHC-type containing 6 -2.57426
ATRN attractin -2.5122
GNAS GNAS complex locus -2.49473
PANK2 pantothenate kinase 2 -2.46301
TMEM230 transmembrane protein 230 -2.4275
GDF15 growth differentiation factor 15 -2.35026
GRWD1 glutamate-rich WD repeat containing 1 -2.28353
HAT1 histone acetyltransferase 1 -2.27649
ZNF638 zinc finger protein 638 -2.21988
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -2.19019
BASP1 brain abundant, membrane attached signal protein 1 -2.16306
DDRGK1 DDRGK domain containing 1 -2.15337
MSN moesin -2.12945
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.0561
MKKS McKusick-Kaufman syndrome -2.05057
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.02022
RPS27L ribosomal protein S27-like -2.00603
EIF3L eukaryotic translation initiation factor 3, subunit L -2.00276