CRCGN016_MCF10A.WT.HP_24H:N03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzene 10.92 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RAB11FIP2 RAB11 family interacting protein 2 (class I) 5.00863
LGMN legumain 4.97082
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.76545
CNPY3 canopy FGF signaling regulator 3 3.60481
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.42475
EMX2 empty spiracles homeobox 2 3.3079
PDLIM1 PDZ and LIM domain 1 2.85897
ARID5B AT rich interactive domain 5B (MRF1-like) 2.8183
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.80806
SPDEF SAM pointed domain containing ETS transcription factor 2.62953
GATA3 GATA binding protein 3 2.44656
FRS2 fibroblast growth factor receptor substrate 2 2.44215
LYN LYN proto-oncogene, Src family tyrosine kinase 2.41973
C5 complement component 5 2.33784
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.30573
COQ8A coenzyme Q8A 2.14743
ELSPBP1 epididymal sperm binding protein 1 2.08852
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.04439
GATA2 GATA binding protein 2 2.04316
RERGL RERG/RAS-like 2.01886
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.00094

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -7.04551
BASP1 brain abundant, membrane attached signal protein 1 -6.19156
ISOC1 isochorismatase domain containing 1 -5.52937
KRT14 keratin 14, type I -4.12145
MTERF3 mitochondrial transcription termination factor 3 -3.26798
TLK2 tousled-like kinase 2 -2.8381
COPS7A COP9 signalosome subunit 7A -2.34655
GAA glucosidase, alpha; acid -2.32308
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.3142
PCNA proliferating cell nuclear antigen -2.3067
REXO2 RNA exonuclease 2 -2.2227
SGK1 serum/glucocorticoid regulated kinase 1 -2.13964
RNF167 ring finger protein 167 -2.13606