CRCGN016_MCF10A.WT.HP_24H:N05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glycidol 33.77 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

45 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.23231
SPAG4 sperm associated antigen 4 4.21185
E2F2 E2F transcription factor 2 4.2008
AGR2 anterior gradient 2 4.07611
LPAR2 lysophosphatidic acid receptor 2 4.06785
KDM5A lysine (K)-specific demethylase 5A 3.48165
PRR7 proline rich 7 (synaptic) 2.95399
PDIA5 protein disulfide isomerase family A, member 5 2.75491
COMP cartilage oligomeric matrix protein 2.63083
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.54329
RBM34 RNA binding motif protein 34 2.46481
IL17B interleukin 17B 2.45935
TIPRL TOR signaling pathway regulator 2.39968
GSK3B glycogen synthase kinase 3 beta 2.38614
SATB1 SATB homeobox 1 2.35208
GMIP GEM interacting protein 2.20868
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 2.19936
HOXA6 homeobox A6 2.19246
GRB14 growth factor receptor-bound protein 14 2.1453
PTPRS protein tyrosine phosphatase, receptor type, S 2.12876
SKI SKI proto-oncogene 2.11936
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.08132
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.06081
EAPP E2F-associated phosphoprotein 2.01099

decreased expression

Symbol Name Standardized Value
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.84407
MAPK13 mitogen-activated protein kinase 13 -4.54531
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.52303
TXNDC9 thioredoxin domain containing 9 -4.34147
HMG20B high mobility group 20B -4.22368
NLRP4 NLR family, pyrin domain containing 4 -3.74043
REEP5 receptor accessory protein 5 -3.41693
SNCA synuclein, alpha (non A4 component of amyloid precursor) -3.22027
TLK2 tousled-like kinase 2 -3.22011
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.06217
NRIP1 nuclear receptor interacting protein 1 -2.66148
PEG10 paternally expressed 10 -2.5145
SGK1 serum/glucocorticoid regulated kinase 1 -2.46698
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.39871
REV1 REV1, polymerase (DNA directed) -2.33402
UNC50 unc-50 homolog (C. elegans) -2.3333
TMEM131 transmembrane protein 131 -2.28066
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.21421
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -2.16842
RAB32 RAB32, member RAS oncogene family -2.10034
RBM15B RNA binding motif protein 15B -2.03698