CRCGN016_MCF10A.WT.HP_24H:N06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glycidol 11.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 4.17801
WASF3 WAS protein family, member 3 3.69212
SNAP25 synaptosomal-associated protein, 25kDa 3.55091
CXCR4 chemokine (C-X-C motif) receptor 4 3.39095
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.21398
INTS3 integrator complex subunit 3 3.1645
CDCA4 cell division cycle associated 4 2.91356
BZW2 basic leucine zipper and W2 domains 2 2.76244
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.34228
BACE2 beta-site APP-cleaving enzyme 2 2.33873

decreased expression

Symbol Name Standardized Value
ANXA2 annexin A2 -4.05489
YME1L1 YME1-like 1 ATPase -3.88376
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.63004
S100A8 S100 calcium binding protein A8 -3.50488
CHMP4B charged multivesicular body protein 4B -3.50365
SCYL3 SCY1-like 3 (S. cerevisiae) -3.23932
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.95822
GDF15 growth differentiation factor 15 -2.78668
BASP1 brain abundant, membrane attached signal protein 1 -2.59808
FAIM Fas apoptotic inhibitory molecule -2.29351
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.28075
WAC WW domain containing adaptor with coiled-coil -2.11579