| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nitrofural 97.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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59 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 5.26746 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.96499 |
| GLOD4 | glyoxalase domain containing 4 | 4.6781 |
| KLHL21 | kelch-like family member 21 | 4.49388 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.36559 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 4.26409 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 3.85607 |
| ANO10 | anoctamin 10 | 3.60612 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.70788 |
| NRBF2 | nuclear receptor binding factor 2 | 2.6347 |
| PEX12 | peroxisomal biogenesis factor 12 | 2.47609 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.47117 |
| BAG5 | BCL2-associated athanogene 5 | 2.46218 |
| GLRX5 | glutaredoxin 5 | 2.43749 |
| ZNF443 | zinc finger protein 443 | 2.41349 |
| LGMN | legumain | 2.41248 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 2.36428 |
| GASK1B | golgi associated kinase 1B | 2.23675 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | 2.20826 |
| SFRP4 | secreted frizzled-related protein 4 | 2.20802 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.17757 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 2.15919 |
| ATP5MJ | ATP synthase membrane subunit j | 2.15128 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 2.1506 |
| TGFBR3 | transforming growth factor, beta receptor III | 2.142 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 2.11139 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 2.10195 |
| COL9A3 | collagen, type IX, alpha 3 | 2.09427 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 2.06256 |
| LEFTY1 | left-right determination factor 1 | 2.04249 |
| SLC25A38 | solute carrier family 25, member 38 | 2.02061 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | 2.00961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -8.14403 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -5.90058 |
| YME1L1 | YME1-like 1 ATPase | -4.72267 |
| CDC45 | cell division cycle 45 | -4.61088 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.41011 |
| BAG3 | BCL2-associated athanogene 3 | -4.15681 |
| TRAPPC3 | trafficking protein particle complex 3 | -3.77337 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -3.50919 |
| CAB39 | calcium binding protein 39 | -3.40946 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -3.35501 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.8526 |
| CDC25C | cell division cycle 25C | -2.74974 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.71286 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | -2.41185 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -2.34926 |
| TEAD3 | TEA domain family member 3 | -2.34698 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -2.31601 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.3093 |
| ABI1 | abl-interactor 1 | -2.28268 |
| HARS1 | histidyl-tRNA synthetase 1 | -2.26005 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.24288 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | -2.21112 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -2.20019 |
| AADAC | arylacetamide deacetylase | -2.19514 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -2.13934 |
| RNF11 | ring finger protein 11 | -2.06175 |
| RAB13 | RAB13, member RAS oncogene family | -2.05057 |