CRCGN016_MCF10A.WT.HP_24H:N08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrofural 32.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GARRE1 granule associated Rac and RHOG effector 1 4.74265
VAV3 vav 3 guanine nucleotide exchange factor 4.50385
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.50656
FAIM Fas apoptotic inhibitory molecule 3.09177
ACAA1 acetyl-CoA acyltransferase 1 3.03917
TMEM50A transmembrane protein 50A 2.85317
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.58856
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.54066
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.17959

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -4.92851
THAP11 THAP domain containing 11 -4.17411
DERA deoxyribose-phosphate aldolase (putative) -3.37542
ACOT9 acyl-CoA thioesterase 9 -2.86267
PRPF4 pre-mRNA processing factor 4 -2.6871
RALGDS ral guanine nucleotide dissociation stimulator -2.3396
ANXA2 annexin A2 -2.32629
TMC5 transmembrane channel-like 5 -2.11331
NGRN neugrin, neurite outgrowth associated -2.00969