CRCGN016_MCF10A.WT.HP_24H:N10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description urethane 105.29 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 5.41511
IDE insulin-degrading enzyme 4.67125
SPAG4 sperm associated antigen 4 3.2596
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.14287
LGMN legumain 2.9178
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.75253
CALML5 calmodulin-like 5 2.51512
SLC38A4 solute carrier family 38, member 4 2.40454
SPDEF SAM pointed domain containing ETS transcription factor 2.39003
LCE2B late cornified envelope 2B 2.3533
KRT2 keratin 2, type II 2.26539
ACSM5 acyl-CoA synthetase medium-chain family member 5 2.06061
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.04132

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -4.5866
RNF167 ring finger protein 167 -3.72791
KIF14 kinesin family member 14 -3.48231
RNF111 ring finger protein 111 -2.32046
REEP5 receptor accessory protein 5 -2.24682
SORBS3 sorbin and SH3 domain containing 3 -2.2219
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -2.15835
CDC42 cell division cycle 42 -2.08185
FAM114A1 family with sequence similarity 114, member A1 -2.04391