CRCGN016_MCF10A.WT.HP_24H:N11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description urethane 35.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.69998
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.4954
EPHB2 EPH receptor B2 3.15391
MAP2K5 mitogen-activated protein kinase kinase 5 2.39188
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.35793
MIS12 MIS12 kinetochore complex component 2.25027

decreased expression

Symbol Name Standardized Value
CHIC2 cysteine-rich hydrophobic domain 2 -5.67952
YME1L1 YME1-like 1 ATPase -5.19982
CANT1 calcium activated nucleotidase 1 -3.23443
DERA deoxyribose-phosphate aldolase (putative) -3.13877
ABI1 abl-interactor 1 -2.94721
CD44 CD44 molecule (Indian blood group) -2.91833
EXOSC4 exosome component 4 -2.75021
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.47901
SERINC1 serine incorporator 1 -2.14225
HTRA1 HtrA serine peptidase 1 -2.03149
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.02837