CRCGN016_MCF10A.WT.HP_24H:N12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description urethane 11.7 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EXOSC4 exosome component 4 4.49503
FAT1 FAT atypical cadherin 1 4.2178
CHEK1 checkpoint kinase 1 4.09545
SATB1 SATB homeobox 1 3.66975
MAMLD1 mastermind-like domain containing 1 3.58893
SIRT3 sirtuin 3 2.96976
COMP cartilage oligomeric matrix protein 2.78673
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.52847
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.46418
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.30299
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.24401
RIC8A RIC8 guanine nucleotide exchange factor A 2.24191
RPP38 ribonuclease P/MRP 38kDa subunit 2.17639
DLAT dihydrolipoamide S-acetyltransferase 2.12859
TXNL4B thioredoxin-like 4B 2.01301

decreased expression

Symbol Name Standardized Value
COG2 component of oligomeric golgi complex 2 -4.40073
CCDC86 coiled-coil domain containing 86 -4.269
GDF15 growth differentiation factor 15 -3.46007
CD58 CD58 molecule -3.39976
RGS2 regulator of G-protein signaling 2 -2.379
HAT1 histone acetyltransferase 1 -2.21957