CRCGN016_MCF10A.WT.HP_24H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinylidene chloride 35.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.43256
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.4241
MYL9 myosin, light chain 9, regulatory 4.32998
ADAM10 ADAM metallopeptidase domain 10 4.20178
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.00976
COMP cartilage oligomeric matrix protein 3.90205
ACAA1 acetyl-CoA acyltransferase 1 3.84513
CXCR4 chemokine (C-X-C motif) receptor 4 3.75276
NUP133 nucleoporin 133kDa 2.98557
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.96907
TIAM1 T-cell lymphoma invasion and metastasis 1 2.82862
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.62978
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.61233
VGLL4 vestigial-like family member 4 2.49057
EVL Enah/Vasp-like 2.39451
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.14395
PLSCR3 phospholipid scramblase 3 2.13054
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 2.12418
OLFML2B olfactomedin-like 2B 2.12089
ADRB2 adrenoceptor beta 2, surface 2.02096
TCEAL4 transcription elongation factor A (SII)-like 4 2.00045

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -6.98482
GDF15 growth differentiation factor 15 -4.67706
BAG3 BCL2-associated athanogene 3 -4.05016
TEX10 testis expressed 10 -3.67659
RNF167 ring finger protein 167 -3.37159
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.3284
YME1L1 YME1-like 1 ATPase -3.16647
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.68115
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.45046
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.41973
ENOPH1 enolase-phosphatase 1 -2.07348
ABI1 abl-interactor 1 -2.04024
WAC WW domain containing adaptor with coiled-coil -2.00939